1
Yuji Iwashita, Katsumi Ajisaka: Blood substitute containing modified hemoglobin. Ajinomoto Company Incorporated, Oblon Fisher Spivak McClelland & Maier, November 17, 1981: US04301144 (419 worldwide citation)

A novel modified hemoglobin was prepared. The hemoglobin is coupled with a polyalkylene glycol or its derivative, and the products are useful as a blood substitute. The oxygen-carrying capacity of this hemoglobin is nearly equal to that of a native hemoglobin, and the residence time in the circulati ...


2
Yuji Iwashita, Katsumi Ajisaka, Keiji Iwasaki: Oxygen carrier. Ajinomoto Company Incorporated, Oblon Fisher Spivak McClelland & Maier, November 1, 1983: US04412989 (214 worldwide citation)

An oxygen carrying material containing hemoglobin or a hemoglobin derivative covalently coupled through an amide bond to a polymer selected from the group consisting of polyethylene glycol, polypropylene glycol, and copolymers of ethylene oxide and propylene oxide.


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Kenji Mizumoto, Hiroshi Tsuboi, Hideki Miyajima, Hiroshi Fujimoto, Katsumi Ajisaka, Yukio Fujiki, Hajime Tsunoo: Anti-HIV agent. Meiji Milk Products, Bacon & Thomas, May 13, 1997: US05629198 (4 worldwide citation)

The invention relates to an anti-HIV agent comprising, as an active ingredient, at least one porphyrin derivative selected from the following derivatives (A) and (B):


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Ikuko Ishii Karakasa, Katsumi Ajisaka: Method for the production of mucin-type glycopeptide. Ikuko Ishii Karakasa, Carol L Francis, Bozicevic Field & Francis, May 25, 2004: US06740509 (2 worldwide citation)

Methods for the production of a mucin-type glycopeptide comprising a transglycosylation using a sugar acceptor such as peptide and a sugar donor as an oligosaccharide with an endo-&agr;-N-acetylgalactosaminidase under a given condition is disclosed. The method provides a new practical way to produce ...


6
Masamichi Takagi, Takahisa Kogure, Naoki Wakisaka, Hiroaki Takaku, Katsumi Ajisaka, Tatsuo Miyazaki, Masao Hirayama: Gene expression cassette and a transformant, and a method for manufacturing 2-deoxy-scyllo-inosose and a method for purifying 2-deoxy-scyllo-inosose using said transformant. Mitsui Chemicals, Niigata Bio Research Park, Buchanan Ingersoll & Rooney PC, June 24, 2014: US08758741 (1 worldwide citation)

A transformant is prepared to insert at least a gene expression cassette comprising a gene involved in the synthesis of 2-deoxy-scyllo-inosose into E. coli as host cells. A 2-deoxy-scyllo-inosose is synthesized from D-glucose, oligosaccharide, polysaccharide, starch and rice bran, using the transfor ...


7
Yoshio Sato, Naoki Taketomo, Yoshihiro Yoshiyama, Katsumi Ajisaka, Itsuro Yokota: Benzofuran derivative and pharmaceutical comprising the same as active ingredient. Meiji Milk Products, Oblon Spivak McClelland Maier & Neustadt, September 14, 1993: US05244918

The present invention relates to a benzofuran derivative having the following general formula (I), ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different and represent a hydrogen atom or a lower alkyl group and R.sup.3 represents a group --CH.dbd.CH--CH.dbd.CH--CH.sub.3 or a group --(CH.s ...


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Ikuko Ishii Karakasa, Katsumi Ajisaka: Method for the production of mucin-type glycopeptide. Bozicevic Field & Francis, November 27, 2003: US20030219851-A1

Methods for the production of a mucin-type glycopeptide comprising a transglycosylation using a sugar acceptor such as peptide and a sugar donor as an oligosaccharide with an endo--N-acetylgalactosaminidase under a given condition is disclosed. The method provides a new practical way to produce muci ...


9
Masamichi Takagi, Takahisa Kogure, Naoki Wakisaka, Hiroaki Takaku, Katsumi Ajisaka, Tatsuo Miyazaki, Masao Hirayama: Gene Expression Cassette and a Transformant, and a Method for Manufacturing 2-Deoxy-Scyllo-Inosose and a Method for Purifying 2-Deoxy-Scyllo-Inosose Using Said Transformant. Niigata Bio Research Center, Mitsui Chemicals, Buchanan Ingersoll & Rooney PC, January 21, 2010: US20100015672-A1

A transformant is prepared to insert at least a gene expression cassette comprising a gene involved in the synthesis of 2-deoxy-scyllo-inosose into E. coli as host cells. A 2-deoxy-scyllo-inosose is synthesized from D-glucose, oligosaccharide, polysaccharide, starch and rice bran, using the transfor ...