1
Kalyan Handique, Karthik Ganesan, Sundaresh N Brahmasandra: Methods and systems for control of microfluidic devices. HandyLab, Fish & Richardson P C, March 7, 2006: US07010391 (127 worldwide citation)

The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined configurations. Such microfluidic devices are preferably constructed in a hierarchical and modular fashion wh ...


2
Betty Wu, Karthik Ganesan, Kalyan Handique, Gene Parunak: Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids. HandyLab, Fish & Richardson P C, March 20, 2007: US07192557 (115 worldwide citation)

The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a lysing zone to receive the cell-containing sample and a positioning element to position the cell-containing sample in a lysing position in the vicinity of a lysing mechanism. The lys ...


3
Karthik Ganesan: Microfluidic devices having a reduced number of input and output connections. Handylab, Fish & Richardson P C, February 8, 2005: US06852287 (106 worldwide citation)

A system and method for reducing the number of input/output connections required to connect a microfluidic substrate to an external controller for controlling the substrate. In one example, a microfluidic processing device is fabricated on a substrate having a plurality of N independently controllab ...


4
Kalyan Handique, Sundaresh N Brahmasandra, Karthik Ganesan, Jeff Williams: Microfluidic system for amplifying and detecting polynucleotides in parallel. HandyLab, Knobbe Martens Olson & Bear, August 16, 2011: US07998708 (74 worldwide citation)

The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. ...


5
Kalyan Handique, Sundaresh N Brahmasandra, Karthik Ganesan, Jeff Williams: Microfluidic system for amplifying and detecting polynucleotides in parallel. HandyLab, Knobbe Martens Olson & Bear, December 4, 2012: US08323900 (65 worldwide citation)

The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. ...


6
Karthik Ganesan: Microfluidic devices having a reduced number of input and output connections. HandyLab, Knobbe Martens Olson & Bear, March 9, 2010: US07674431 (55 worldwide citation)

A system and method for reducing the number of input/output connections required to connect a microfluidic substrate to an external controller for controlling the substrate. In one example, a microfluidic processing device is fabricated on a substrate having a plurality of N independently controllab ...


7
Karthik Ganesan, Kalyan Handique: Systems and methods for thermal actuation of microfluidic devices. HandyLab, Knobbe Martens Olson & Bear, April 16, 2013: US08420015 (53 worldwide citation)

A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component ...


8
Karthik Ganesan: Method of controlling a microfluidic device having a reduced number of input and output connections. HandyLab, Knobbe Martens Olson & Bear, December 4, 2012: US08323584 (51 worldwide citation)

A system and method for reducing the number of input/output connections required to connect a microfluidic substrate to an external controller for controlling the substrate. A microfluidic processing device is fabricated on a substrate having a plurality of N independently controllable components, ( ...


9
Kalyan Handique, Karthik Ganesan, Sundaresh N Brahmasandra: Methods and systems for control of microfluidic devices. Handylab, Knobbe Martens Olson & Bear, June 25, 2013: US08473104 (47 worldwide citation)

The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined configurations. Such microfluidic devices are preferably constructed in a hierarchical and modular fashion wh ...


10
Kalyan Handique, Karthik Ganesan, Sundaresh N Brahmasandra: Methods and systems for control of general purpose microfluidic devices. HandyLab, Knobbe Martens Olson & Bear, November 25, 2014: US08895311 (30 worldwide citation)

The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined configurations. Such microfluidic devices are preferably constructed in a hierarchical and modular fashion wh ...