1
Robert C Chang, Kari I Kivirikko, Thomas B Neff, David R Olsen, James W Polarek: Recombinant gelatins. FibroGen, James E Nesbitt, Leanne C Price, FibroGen, January 31, 2006: US06992172 (82 worldwide citation)

The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.


2
Darwin J Prockop, Leena Ala Kokko, Andrzej Fertala, Aleksander Sieron, Kari I Kivirikko, Amy Geddis, Taina Pihlajaniemi: Synthesis of human procollagens and collagens in recombinant DNA systems. Thomas Jefferson University, Albert P Pennie & Edmonds Halluin Esq, January 14, 1997: US05593859 (19 worldwide citation)

The invention is transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said collag ...


3
Thomas Neff, George Martin, Karl A Piez, Taina Pihlajaniemi, Kari I Kivirikko: Collagen-based methods and formulations for the treatment of arthritis. FibroGen, Pennie & Edmonds, July 20, 1999: US05925736 (11 worldwide citation)

The invention provides novel methods and compositions for the treatment of immune system-mediated arthritis, including rheumatoid arthritis. The subject compositions comprise one or more different types of collagen or collagen derivatives and a mucosa binding structure. Specific combinations of coll ...


4
Darwin J Prockop, Leena Ala Kokko, Andrzej Fertala, Aleksander Sieron, Kari I Kivirikko, Amy Geddis: Synthesis of human procollagens and collagens in recombinant DNA systems. Thomas Jefferson University, Woodcock Washburn Kurtz Mackiewicz & Norris, April 11, 1995: US05405757 (8 worldwide citation)

The invention is stably transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said ...


5
Stephan Henke, Dietrich Brocks, Volkmar Gunzlen Pukall, Kari I Kivirikko, Raili M H Myllyla: Oligopetides with cyclic proline-analogous amino acids. Hoechst Aktiengesellschaft, Finnegan Henderson Farabow Garrett & Dunner, April 27, 1993: US05206343 (6 worldwide citation)

The invention relates to compounds of the formula I ##STR1## in which A denotes an optionally substituted radical from the series comprising alkyl, acyl, cycloalkyl, aryl and heteroaryl; Cyc represents an optionally substituted heterocyclic carbonyl compound; D represents NH, NCH.sub.3, O or CH.sub. ...


6
Robert C Chang, Kari I Kivirikko, Thomas B Neff, David R Olsen, James W Polarek: Recombinant gelatins. FibroGen, James E Nesbitt, July 1, 2008: US07393928 (1 worldwide citation)

The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.


7

8
Darwin J Prockop, Leena Ala Kokko, Andrzej Fertala, Aleksander Sieron, Kari I Kivirikko, Amy Geddis, Taina Pihlajaniemi: Synthesis of human procollagens and collagens in recombinant dna systems. Robins & Pasternak, July 25, 2002: US20020098578-A1

The invention is transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said collag ...


9
Robert C Chang, Kari I Kivirikko, Thomas B Neff, David R Olsen, James W Polarek: Recombinant gelatins in vaccines. FibroGen, April 3, 2003: US20030064074-A1

The present invention relates to vaccines comprising recombinant gelatin, to methods of producing and using such vaccines, and to vaccination kits.


10
Kari I Kivirikko, Taina Pihlajaniemi, Tarja Inkeri Helaakoski, Pia Pauliina Annunen, Ritva Kaarina Nissi, Minna Kristiina Nokelainen: Alpha2 subunit of prolyl 4-hydroxylase. FibroGen, November 28, 2002: US20020177203-A1

The present invention relates to novel isoforms of the subunit of prolyl 4-hydroxylase, polynucleotide sequences encoding these novel proteins, and methods for making such proteins.



Click the thumbnails below to visualize the patent trend.