1
Cheng Hengmiao, Cui Jingrong Jean, Hoffman Jacqui Elizabeth, Jia Lei, Kania Robert Steven, Le Phuong Thi Quy, Nambu Mitchell David, Pairish Mason Alan, Shen Hong, Tran Dube Michelle Bich: Triazolopyridazine derivatives. Pfizer Products, Cheng Hengmiao, Cui Jingrong Jean, Hoffman Jacqui Elizabeth, Jia Lei, Kania Robert Steven, Le Phuong Thi Quy, Nambu Mitchell David, Pairish Mason Alan, Shen Hong, Tran Dube Michelle Bich, FULLER Grover F Jr, December 6, 2007: WO/2007/138472 (40 worldwide citation)

The invention relates to compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R3' are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of treating hyperproliferative disor ...


2

3
Cheng Hengmiao, Cui Jingrong Jean, Hoffman Jacqui Elizabeth, Jia Lei, Johnson Mary Catherine, Kania Robert Steven, Le Phuong Thi Quy, Nambu Mitchell David, Pairish Mason Alan, Shen Hong, Tran Dube Michelle Bich: Triazolopyrazine derivatives useful as anti-cancer agents. Pfizer Products, Cheng Hengmiao, Cui Jingrong Jean, Hoffman Jacqui Elizabeth, Jia Lei, Johnson Mary Catherine, Kania Robert Steven, Le Phuong Thi Quy, Nambu Mitchell David, Pairish Mason Alan, Shen Hong, Tran Dube Michelle Bich, FULLER Grover F Jr, November 22, 2007: WO/2007/132308 (27 worldwide citation)

The invention relates to compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorder ...


4
He Mingying, Kania Robert Steven, Lou Jihong: Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents. Pfizer, He Mingying, Kania Robert Steven, Lou Jihong, FULLER Grover F Jr, March 10, 2005: WO/2005/021554 (17 worldwide citation)

The invention relates to compounds represented by Formula (I):, and to prodrugs thereof, pharmaceutically salts or solvates of said compounds or said prodrugs, wherein each of X1-X5 and R1-R5 are defined herein. The invention also relates to pharmaceutical compositions containing the compounds of Fo ...


5
He Mingying, Kania Robert Steven, Lou Jihong, Zhou Ru: Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents. Pfizer, He Mingying, Kania Robert Steven, Lou Jihong, Zhou Ru, FULLER Grover F Jr, March 10, 2005: WO/2005/021553 (10 worldwide citation)

The invention relates to compounds represented by Formula (I) and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein each of R1a-d , R2a-b , R3, and X1 are defined herein, The invention also relates to pharmaceutical compositions containing ...


6
Hong Yufeng, Kania Robert Steven: Novel quinoline derivatives. Pfizer, Hong Yufeng, Kania Robert Steven, FULLER Grover F Jr, July 14, 2005: WO/2005/063739 (9 worldwide citation)

The invention relates to compounds represented by Formula (I): and to pharmaceutically acceptable salts or solvates of said compounds, wherein each of A, R3-8, X3, X5, m, and n are defined herein. The invention also relates to pharmaceutical compositions containing the compounds of Formula (I) and t ...


7

8
Chu Shao Song, Alegria Larry Andrew, Bender Steven Lee, Benedict Suzanne Pritchett, Borchardt Allen J, Kania Robert Steven, Nambu Mitchell David, Tempczyk Russell Anna Maria, Sarshar Sepehr, Bhumralkar Dilip, Peng Zhengwei, Yang Yi Michelle: Diaminothiazoles and their use for inhibiting protein kinases. Agouron Pharmaceuticals, PINO Mark J, December 14, 2000: WO/2000/075120 (4 worldwide citation)

Diaminothiazole compounds of formula (I) that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction in order to modulate and/or inhibit unwanted cell ...


9
Borchardt Allen John, Kania Robert Steven, Palmer Cynthia Louise: 2-(1h-indazol-6-ylamino)-benzamide compounds as protein kinases inhibitors useful for the treatment of ophtalmic diseases. Pfizer, Borchardt Allen John, Kania Robert Steven, Palmer Cynthia Louise, LUMB J Trevor, July 8, 2004: WO/2004/056806 (4 worldwide citation)

Indazole compounds that modulate and/or inhibit the ophthalmic diseases and the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted ...


10
Kania Robert Steven, Bender Steven Lee, Borchardt Allen J, Braganza John F, Cripps Stephan James, Hua Ye, Johnson Michael David, Johnson Theodore Otto Jr, Luu Hiep The, Palmer Cynthia Louise, Reich Siegfried Heinz, Tempczyk Russell Anna Maria, Teng Min, Thomas Christine, Varney Michael David, Wallace Michael Brennan, Collins Michael Raymond: Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use. Agouron Pharmaceuticals, PINO Mark J, January 11, 2001: WO/2001/002369 (3 worldwide citation)

Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The inv ...