1
Okada Hiroaki, Kamei Shigeru, Yoshioka Toshio: Intravascular embolizing agent containing angiogenesis inhibiting substance.. Takeda Chemical Industries, February 12, 1992: EP0470569-A1 (109 worldwide citation)

The present invention relates to an intravascular embolizing agent containing an angiogenesis-inhibiting substance and an intravascular embolizing substance. The agent strengthens the antitumor effect of an angiogenesis-inhibiting substance and serves to reduce the dose and undesirable side effects. ...


2
Kamei Shigeru, Ogawa Yasuaki Koaza Tanita, Yamada Minoru: Method of producing sustained-release microcapsules.. Takeda Chemical Industries, March 9, 1994: EP0586238-A2 (22 worldwide citation)

A method of producing sustained-release microcapsules containing a biologically active substance from an W/O emulsion comprising an inner aqueous phase containing said biologically active substance and an external oil phase containing a biodegradable polymer, characterized in that microcapsules form ...


3
Kamei Shigeru, Igari Yasutaka, Ogawa Yasuaki: Sustained-release preparation.. Takeda Chemical Industries, June 15, 1994: EP0601799-A1 (21 worldwide citation)

A sustained-release preparation which comprises a physiologically active peptide of general formula wherein X represents an acyl group; R1, R2 and R4 each represents an aromatic cyclic group; R3 represents a D-amino acid residue or a group of the formula wherein R3' is a heterocyclic group; R5 repre ...


4
Kamei Shigeru, Yoshioka Toshio, Okada Hiroaki: Stabilized composition of anthracyclines.. Takeda Chemical Industries, October 17, 1990: EP0392487-A2 (14 worldwide citation)

The present invention relates to a pharmaceutical composition containing an anthracycline antibiotic having an amino sugar residue and a water-soluble polyanion capable of at least 40% interacting with said antibiotic. In the composition according to the invention, the anthracycline antibiotic is st ...


5
Kamei Shigeru, Okada Hiroaki, Sudo Katsuichi, Kishimoto Shoji: Cyclodextrin complex.. Takeda Chemical Industries, December 18, 1991: EP0461427-A2 (10 worldwide citation)

A complex of a fumagillin derivative represented by the general formula: wherein R is hydrogen; R is halogen, N(O)mRR, NRRR . X, S(O)nR or SRR . X (wherein R, R and R are independently an optionally substituted hydrocarbon or heterocyclic group; X is a counter anion; m is an integer of 0 or 1; n is ...


6
Igari Yasutaka, Saikawa Akira, Okamoto Kayoko, Kamei Shigeru, Oka Masahisa, Sano Atsunori: Polyester matrix for a pharmaceutical sustained-release preparation.. Takeda Chemical Industries, Wako Pure Chem, August 23, 1995: EP0668073-A2 (8 worldwide citation)

The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an alpha -hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is o ...


7
Sueyoshi Masahiko, Kamei Shigeru, Yuhi Kazuo, Asakura Suguru, Kamikura Akira, Yoshimura Kentaro, Ishikawa Kiyomitsu, Sugimura Kazuhiko: Vehicle outer handle system. Honda Lock, Honda Motor, Stanley Electric, October 2, 2002: EP1245761-A2 (6 worldwide citation)

A vehicle outer handle system includes a handle main body (7) formed from a synthetic resin and having a hollow grip part (7a), and an electrode (21) for detecting a change in capacitance. One end of the handle main body is swingably supported in a door outer panel (6), and the electrode is housed w ...


8
Igari Yasutaka, Kamei Shigeru: Medicinal preparations for treating sex hormone-dependent diseases. Takeda Chemical Industries, April 2, 2003: EP1297850-A1 (6 worldwide citation)

Medicinal preparations for treating sex hormone-dependent diseases which comprise a combination of a compound having a luteinizing hormone-releasing hormone agonistic effect or its salt with a compound having a luteinizing hormone-releasing hormone antagonistic effect or its salt for administering t ...


9
Kamei Shigeru, Ojima Mami, Kitayoshi Takahito, Igari Yasutaka: Sustained release preparations of physiologically active compound hardly soluble in water and production process and use of the same. Takeda Chemical Industries, November 20, 2002: EP1258254-A1 (5 worldwide citation)

A sustained-release preparation containing a physiologically active compound slightly soluble in water, a component obtained by treating with water a polyvalent metal compound slightly soluble in water, and a biodegradable polymer which are improved in the release-control and stabilization of the ph ...


10
Kamei Shigeru, Watanabe Yoshimi: Method and device for mounting components on a printed circuit board.. Tokyo Shibaura Electric Co, December 4, 1991: EP0459831-A2 (3 worldwide citation)

A printed circuit board apparatus comprises a printed circuit board. The printed circuit board includes a first and a second surface and a hole portion. A printed pattern is formed on the first surface, and a parts having a lead is mounted on the second surface. The printed circuit board apparatus a ...