1
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation. Mercator MedSystems, Townsend and Townsend and Crew, June 29, 2010: US07744584 (39 worldwide citation)

Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent suff ...


2
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation. Mercator MedSystems, Wilson Sonsini Goodrich & Rosati, April 29, 2014: US08708995 (27 worldwide citation)

Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent suff ...


3
Kirk Patrick Seward, Lynn Barr, Judith Carol Wilber: Methods and systems for delivering liquid substances to tissues surrounding body lumens. Mercator Medsystems, Townsend and Townsend and Crew, December 16, 2008: US07465298 (18 worldwide citation)

Methods, systems, and apparatus for delivering drugs and other substances to extraluminal tissue surrounding a body lumen are described. Catheters are used to inject the drug or other substance intraluminally into tissue surrounding a stent or other luminal scaffold. The drug or other substance is i ...


4
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation. MERCATOR MEDSYSTEMS, Wilson Sonsini Goodrich & Rosati, June 23, 2015: US09061098 (1 worldwide citation)

Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent suff ...


5
Judith Carol Wilber, Lynn Mateel Barr, Kirk Patrick Seward: Methods and systems for treating the vasculature with estrogens. EndoBionics, Townsend And Townsend And Crew, August 19, 2004: US20040162542-A1

Methods and systems for inhibiting neointimal hyperplasia and treating vulnerable plaque comprise direct needle injection of estrogen into a perivascular space or adventitial tissue.


6
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation. EndoBionics, Townsend And Townsend And Crew, July 15, 2004: US20040138643-A1

Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent suff ...


7
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia. Mercator MedSystems, Townsend And Townsend And Crew, May 10, 2007: US20070106257-A1

Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood ...


8
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia. Mercator MedSystems, Townsend And Townsend And Crew, May 10, 2007: US20070106248-A1

Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood ...


9
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia. Mercator MedSystems, Townsend And Townsend And Crew, May 10, 2007: US20070106249-A1

Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood ...


10
Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia. Mercator MedSystems, Townsend And Townsend And Crew, May 10, 2007: US20070106250-A1

Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood ...