1
Joseph H Schulman, Orville R Rule III, David I Whitmoyer, Ronald J Lebel, Joseph Y Lucisano, Alfred E Mann: Glucose monitoring system. Alfred E Mann Foundation For Scientific Research, Fitch Even Tabin & Flannery, March 12, 1996: US05497772 (1109 worldwide citation)

A glucose monitoring system continuously measures the glucose concentration in a patient's blood, provides an indication of the rate of change of such concentration, and determines whether the measured concentration and rate of change are within certain preset limits. If not, an audible and/or visua ...


2
Joseph H Schulman, Ronald J Lebel, Joseph Y Lucisano, Alfred E Mann, Orville Rey Rule III, David I Whitmoyer: Patient monitoring system. Alfred E Mann Foundation for Scientific Research, Fitch Even Tabin & Flannery, August 11, 1998: US05791344 (1051 worldwide citation)

A patient monitoring system measures the concentration of a particular substance in a patient's tissue, blood, or other bodily fluids, provides an indication of the rate of change of such concentration, and determines whether the measured concentration and rate of change are within certain preset li ...


3
David A Gough, Joseph Y Lucisano, Jon C Armour, Brian D McKean: Complete glucose monitoring system with an implantable, telemetered sensor module. The Regents of the University of California, Brown Martin Haller & Meador, November 3, 1987: US04703756 (976 worldwide citation)

An electrochemical system includes a sensor module suitable for implantation in the body to monitor glucose and oxygen levels therein. The module has two oxygen sensors situated in an oxygen-permeable housing, arranged in a tandem relationship, and recessed in the housing, one sensor being unaltered ...


4
Joseph H Schulman, Orville Rey Rule III, David I Whitmoyer, Ronald J Lebel, Joseph Y Lucisano, Alfred E Mann: Glucose sensor assembly. Alfred E Mann Foundation for Scientific Research, Fitch Even Tabin & Flannery, August 26, 1997: US05660163 (926 worldwide citation)

A glucose monitoring system continuously measures the glucose concentration in a patient's blood, provides an indication of the rate of change of such concentration, and determines whether the measured concentration and rate of change are within certain preset limits. If not, an audible and/or visua ...


5
Joseph H Schulman, Joseph Y Lucisano, Rajiv Shah, Charles L Byers, Shaun M Pendo: Alumina insulation for coating implantable components and other microminiature devices. Alfred E Mann Foundation, Abraham N Seidman, March 28, 2000: US06043437 (352 worldwide citation)

A protective, biocompatible coating or encapsulation material protects and insulates a component or device intended to be implanted in living tissue. The coating or encapsulation material includes a thin layer or layers of alumina, zirconia, or other ceramic, less than 25 microns thick, e.g., 5-10 m ...


6
David K Wong, Joseph Y Lucisano: Electrode assembly for assaying glucose. Via Medical Corporation, Sheppard Mullin Richter & Hampton, September 8, 1998: US05804048 (339 worldwide citation)

An improved electrode assembly is disclosed for use in assaying glucose in solution, e.g., in undiluted whole blood. The assembly includes a sensor electrode and a special overlaying multi-layer membrane that can be sterilized by gamma radiation without reducing the activity of a glucose oxidase enz ...


7
Joseph H Schulman, Joseph Y Lucisano, Rajiv Shah, Charles L Byers, Shaun M Pendo: Method of applying insulation for coating implantable components and other microminiature devices. Medtronic Minimed, Foley & Lardner, October 29, 2002: US06472122 (330 worldwide citation)

A protective, biocompatible coating or encapsulation material protects and insulates a component or device intended to be implanted in living tissue. The coating or encapsulation material comprises a thin layer or layers of alumina, zerconia, or other ceramic, less than 25 microns thick, e.g., 5-10 ...


8
David A Gough, Joseph Y Lucisano: Method for increasing the service life of an implantable sensor. The Regents of the University of California, Brown Martin Haller & McClain, November 16, 1999: US05985129 (263 worldwide citation)

Methods are described for extending the service life of implantable sensors having a silver-containing anodic reference electrode maintained at a high impedance, at least one noble metal cathodic working electrode, and at least one noble metal anodic counter electrode maintained at a low impedance, ...


9
Joseph H Schulman, Joseph Y Lucisano, Rajiv Shah, Charles L Byers, Shaun M Pendo: Alumina insulation for coating implantable components and other microminiature devices. Medtronic Minimed, Foley & Lardner, January 18, 2005: US06844023 (154 worldwide citation)

A protective, biocompatible coating or encapsulation material protects and insulates a component or device intended to be implanted in living tissue. The coating or encapsulation material comprises a thin layer or layers of alumina, zirconia or other ceramic, less than 25 microns thick, e.g., 5-10 m ...


10
Wallace L Knute deceased, David K Wong, Joseph Y Lucisano, Thomas J Carlisle, Alfonso Del Toro: Sensor apparatus for use in measuring a parameter of a fluid sample. Via Medical Corporation, James R Brueggemann, Sheppard Mullin Richter & Hampton, August 3, 1999: US05932175 (72 worldwide citation)

An improved sensor apparatus of a kind that positions a semi-permeable membrane adjacent to an electrode assembly, for measuring a predetermined parameter, e.g., glucose concentration, of an adjacent fluid sample. A special compressible ring serves a first function of tensioning the membrane so that ...