1
Joseph M Pastore, Zoe Harris Hajenga, Julio C Spinelli: Multi-site ventricular pacing therapy with parasympathetic stimulation. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, February 2, 2010: US07657312 (87 worldwide citation)

A method and device for delivering multi-site ventricular pacing therapy in conjunction with parasympathetic stimulation for reducing ventricular wall stress. Such reduction in ventricular wall stress is useful in reversing or preventing the ventricular remodeling which can occur in heart failure pa ...


2
Joseph M Pastore, Rodney W Salo, Quan Ni, Qingsheng Zhu, Jiang Ding: Method and apparatus for detecting oscillations in cardiac rhythm. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, May 2, 2006: US07039462 (78 worldwide citation)

A cardiac rhythm management device is configured to detect mechanical oscillations in cardiac rhythm. Upon detection of such oscillations, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.


3
Joseph M Pastore, Steven D Girouard: Methods and apparatuses for localizing myocardial infarction during catheterization. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, December 29, 2009: US07640046 (78 worldwide citation)

A catheter with a tissue property sensor provides for localization of myocardial infarction (MI) by utilizing one or more differences between properties of infarcted myocardial tissue and properties of normal myocardial tissue. The tissue property sensor is to be placed on endocardial wall or epicar ...


4
Joseph M Pastore, Tamara Colette Baynham, Andrew P Kramer, Julio C Spinelli, Jeffrey Ross, Rodney W Salo: Myocardium conditioning using myocardial and parasympathetic stimulation. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, March 30, 2010: US07689286 (66 worldwide citation)

Various system embodiments comprise a neural stimulator, a pulse generator, and a controller. The neural stimulator is adapted to generate a neural stimulation signal. The pulse generator is adapted to generate a pacing signal to provide myocardium pacing. The controller is adapted to control the ne ...


5
Yinghong Yu, Jiang Ding, Joseph M Pastore: Dynamic device therapy control for treating post myocardial infarction patients. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, May 8, 2007: US07215997 (56 worldwide citation)

A cardiac rhythm management system includes an implantable device executing a dynamic pacing algorithm after an myocardial infarction (MI) event. The dynamic pacing algorithm dynamically adjusts one or more pacing parameters based on a person's gross physical activity level. Examples of the one or m ...


6
Joseph M Pastore, Steven D Girouard: Method and apparatus for assessing and treating myocardial wall stress. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, November 15, 2005: US06965797 (52 worldwide citation)

An apparatus and method for assessing myocardial wall stress is disclosed. The method may be used in conjunction with electro-stimulatory therapy for preventing or reversing ventricular remodeling. In such therapy, one or more stimulatory pulses are delivered to the heart such that a stressed region ...


7
Imad Libbus, Julio C Spinelli, Joseph M Pastore, Andrew P Kramer: Physical conditioning system, device and method. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, January 12, 2010: US07647101 (52 worldwide citation)

Various system embodiments comprise a neural stimulator and a controller. The neural stimulator is adapted to generate a stimulation signal adapted to elicit sympathetic activity at a neural target. The controller is adapted to control the neural stimulator to provide a physical conditioning therapy ...


8
Frits Prinzen, Richard Cornelussen, Ward Vanagt, Joseph M Pastore, Julio C Spinelli: Intermittent stress augmentation pacing for cardioprotective effect. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, November 13, 2007: US07295874 (49 worldwide citation)

A device and method for delivering electrical stimulation to the heart in a manner which provides a protective effect against subsequent ischemia is disclosed. The protective effect is produced by configuring a cardiac pacing device to intermittently switch from a normal operating mode to a stress a ...


9
Joseph M Pastore, William C Lincoln, Gerrard M Carlson, Qingsheng Zhu, Jiang Ding: Method and apparatus for detecting acoustic oscillations in cardiac rhythm. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, September 26, 2006: US07113825 (46 worldwide citation)

A cardiac rhythm management device is configured to detect oscillations in cardiac rhythm by measuring the amplitudes of heart sounds during successive heart beats. Upon detection of acoustic alternans, the device may adjust its operating behavior to compensate for the deleterious effects of the con ...


10
Joseph Walker, Rodney W Salo, Anand Iyer, Joseph M Pastore, Eric Mokelke: Systems and methods for electrical stimulation of blood vessels. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, May 14, 2013: US08442639 (32 worldwide citation)

Disclosed herein, among other things, is a system for electrical stimulation of blood vessels. An embodiment of the system includes at least one electrode having electrical contact with a blood vessel. The embodiment also includes a stimulation circuit electrically connected to the electrode, the ci ...