1
Patrick S L Wong, Brian Barclay, Joseph C Deters, Felix Theeuwes: Osmotic device with dual thermodynamic activity. Alza Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, September 16, 1986: US04612008 (327 worldwide citation)

An osmotic system is disclosed comprising a wall formed in at least a part of a semipermeable material that surrounds a compartment. The compartment contains a first osmotic composition comprising a beneficial agent, and a second and different osmotic composition. A passageway in the wall connects t ...


2
Patrick S L Wong, Brian L Barclay, Joseph C Deters, Felix Theeuwes: Osmotic device for administering certain drugs. Alza Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, August 23, 1988: US04765989 (200 worldwide citation)

An osmotic system is disclosed comprising a wall comprising in at least a part of a semipermeable material that surrounds a compartment. The compartment contains an osmotic composition comprising a beneficial drug selected from the group consisting of nifedipine, prazosin and doxazosin, and a second ...


3
Joseph C Deters, Felix Theeuwes, Kevin J Mullins, James B Eckenhoff: Osmotic capsule. ALZA Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, December 9, 1986: US04627850 (148 worldwide citation)

An osmotic capsule is disclosed for delivering a beneficial agent formulation to an environment of use. The osmotic capsule comprises an outer semipermeable wall surrounding and laminating an inner capsule wall formed of a different polymeric composition than the outer wall. The walls define an inte ...


4
George V Guittard, Joseph C Deters, Felix Theeuwes, Richard Cortese: Osmotic system with instant drug availability. ALZA Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, March 18, 1986: US04576604 (106 worldwide citation)

An osmotic device is disclosed for delivering a beneficial agent. The device comprises a wall surrounding a compartment containing an agent, a passageway in the wall connecting the exterior of the device with the compartment, and (a) an agent in the wall or (b) an agent carried on the wall in the wa ...


5
Patrick S L Wong, Brian L Barclay, Joseph C Deters, Felix Theeuwes: Controlled-release system with constant pushing source. Alza Corporation, Paul L Sabatine, Edward L Mandell, Jacqueline S Larson, January 21, 1992: US05082668 (72 worldwide citation)

A device is disclosed comprising a wall that surrounds a compartment. The compartment comprises a beneficial agent composition and a push composition. A passageway in the wall connects the compartment with the exterior of the device for delivering the beneficial agent at a rate governed, in combinat ...


6
George V Guittard, Joseph C Deters, Felix Theeuwes, Richard Cortese: Osmotic system with instant drug availability. Alza Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, June 16, 1987: US04673405 (72 worldwide citation)

An osmotic device is disclosed for delivering a beneficial agent. The device comprises a wall surrounding a compartment containing drug, a passageway in the wall connecting the exterior of the device with the compartment, and drug in the wall. The device delivers the drug from the compartment and th ...


7
James B Eckenhoff, Felix Theeuwes, Joseph C Deters: Dispenser comprising telescopically engaging members. ALZA Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, May 5, 1987: US04663148 (32 worldwide citation)

A dispenser is disclosed for delivering a beneficial agent to an environment of use. The dispenser comprises a semipermeable wall surrounding a compartment containing a heat responsive composition, and an expandable composition. A passageway in the wall connects the compartment with the exterior of ...


8
Joseph C Deters, Patrick S L Wong, Brian L Barclay, Felix Theeuwes, David R Swanson: Dosage form for dispensing drug for human therapy. ALZA Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, June 6, 1989: US04837111 (29 worldwide citation)

An osmotic dosage system is disclosed for delivering the therapeutically beneficial drug doxazosin to an environment of use over time.


9
Atul D Ayer, Terry L Burkoth, Anthony L Kuczynski, Joseph C Deters: Controlled release dispenser comprising beneficial agent. Alza Corporation, Jacqueline S Larson, Paul L Sabatine, Steven F Stone, December 28, 1993: US05273752 (25 worldwide citation)

A dispenser is disclosed for delivering a beneficial agent in a hydrophilic carrier formulation to an animal in a rate-controlled manner. The dispenser comprises (1) a semipermeable housing defining an internal space, (2) at least one composition comprising a beneficial agent and a pharmaceutically ...


10
James B Eckenhoff, Felix Theeuwes, Joseph C Deters: Drug dispenser comprising a multiplicity of members acting together for successfully dispensing drug. ALZA Corporation, Paul L Sabatine, Edward L Mandell, Steven F Stone, December 29, 1987: US04716031 (24 worldwide citation)

A dispenser is disclosed for delivering a beneficial agent to an environment of use. The dispenser comprises a semipermeable wall surrounding a compartment containing a heat responsive composition, and an expandable composition. A passageway in the wall connects the compartment with the exterior of ...