1
Tarran Jones
Mary M Bendig, Olivier J Leger, Jose Saldanha, S Tarran Jones, Ted A Yednock: Humanized antibodies against leukocyte adhesion molecule VLA-4. Athena Neurosciences, Townsend & Townsend & Crew, November 24, 1998: US05840299 (78 worldwide citation)

The invention provides humanized immunoglobulins that specifically bind to the VLA-4 ligand, and methods of treatment using the same. The methods are particularly useful for treatment of multiple sclerosis.


2
Tarran Jones
Mary M Bendig, Olivier J Leger, Jose Saldanha, Tarran S Jones, Ted A Yednock: Methods of inhibiting alpha-4-dependent interactions with VCAM-1 with anti-VLA-4 antibodies. Elan Pharmaceuticals, Crowell & Moring, August 21, 2012: US08246958 (31 worldwide citation)

The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host ...


3
Tarran Jones
Mary M Bendig, Olivier J Leger, Jose Saldanha, Tarran S Jones, Ted A Yednock: Humanized anti-VLA4 immunoglobulins. Elan Pharaceuticals, Crowell & Moring, October 14, 2008: US07435802 (6 worldwide citation)

The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host ...


4

5
Mary M Bendig, Catherine A Kettleborough, Jose Saldanha: Humanized and chimeric anti-epidermal growth factor receptor monoclonal antibodies. Merck Patent Gesellschaft Mit Beschrankter Haftung, Millen White Zelano & Branigan P C, September 24, 1996: US05558864 (153 worldwide citation)

Humanized and chimeric anti-epidermal growth factor receptor (anti-EGF-R) monoclonal antibodies are disclosed, comprising an artificial modified consensus sequence for the heavy chain of the framework region of the variable region of a human immunoglobulin. Corresponding humanized and chimeric monoc ...


6
Guriq Basi, Jose Saldanha: Humanized antibodies that recognize beta amyloid peptide. Elan Pharma International, Wyeth, Lahive & Cockfield, Amy E Mandragouras Esq, Debra J Milasincic Esq, August 14, 2007: US07256273 (60 worldwide citation)

The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Preferred agents include humanized antibodies.


7
Norman Hardman, Frank Kolbinger, Jose Saldanha: Reshaped monoclonal antibodies against an immunoglobulin isotype. Novartis Corporation, Tanox Biosystems, Gregory D Ferraro, June 6, 2000: US06072035 (15 worldwide citation)

The invention relates to reshaped human monoclonal antibodies directed against isotypic determinants of immunoglobulin E (IgE), direct equivalents and derivatives of said antibodies. The molecules of the invention are useful for diagnostics, prophylaxis and treatment of allergy.


8
Norman Hardman, Frank Kolbinger, Jose Saldanha: Reshaped monoclonal antibodies against an immunoglobulin isotype. Novartis Corporation, Tanox Biosystems, Gregory D Ferraro, September 28, 1999: US05958708 (15 worldwide citation)

The invention relates to reshaped human monoclonal antibodies directed against isotypic determinants of immunoglobulin E (IgE), direct equivalents and derivatives of said antibodies. The molecules of the invention are useful for diagnostics, prophylaxis and treatment of allergy.


9
Guriq Basi, Jose Saldanha, Frédérique Bard: Humanized antibodies that recognize beta amyloid peptide. Janssen Alzheimer Immunotherapy, Wyeth, Alston and Bird, January 18, 2011: US07871615 (14 worldwide citation)

The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Preferred agents include antibodies, e.g., humanized antibodies.


10
Norman Hardman, Frank Kolbinger, Jose Saldanha: Reshaped monoclonal antibodies against an immunoglobulin isotype. Novartis Corporation, Tanox Biosystems, Gregory D Ferrar, May 23, 2000: US06066718 (11 worldwide citation)

The invention relates to reshaped human monoclonal antibodies directed against isotypic determinants of immunoglobulin E (IgE), direct equivalents and derivatives of said antibodies. The molecules of the invention are useful for diagnostics, prophylaxis and treatment of allergy.



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