1
Axel F Brisken, John R McKenzie, Robert F Zuk, Menahem Nassi, Mark W Cowan, Paul D Corl: Therapeutic ultrasonic catheter for delivering a uniform energy dose. Pharmasonics, Townsend and Townsend and Crew, October 2, 2001: US06296619 (345 worldwide citation)

A method of treating a target region in a body lumen, said method comprising: directing a uniform dose of ultrasonic energy from an interior of the lumen radially outward over a treatment length of the lumen, wherein the dosage of ultrasonic energy received at any one point along the length varies b ...


2
James J Leary, John R McKenzie: Ultrasonic imaging catheter with guidewire channel. Cardiovascular Imaging Systems, Townsend and Townsend, June 18, 1991: US05024234 (199 worldwide citation)

Intravascular catheters including both a flexible catheter body and a less flexible housing mounted at a distal end of the catheter body are provided with a flexible distal tip, preferably having a conical geometry. Guidewire channel or lumen is formed within the tip, and optionally additional guide ...


3
Axel F Brisken, Robert Zuk, John R McKenzie, Mark W Cowan: Methods and apparatus for uniform transcutaneous therapeutic ultrasound. Pharmasonics, Townsend and Townsend and Crew, June 10, 2003: US06575956 (114 worldwide citation)

A wide beam ultrasound delivery system providing a uniform exposure field is used to enhance the uptake of injected substances and/or to enhance the transfection of DNA in the tissues of human subject, or reduce the amount of vascular intimal hyperplasia in human subjects following vascular injury.


4
Stephen M Salmon, John R McKenzie, Peter Thornton, Richard Ginn: Expandable member for a catheter system. Cardiovascular Imaging Systems, Townsend and Townsend Khourie and Crew, May 24, 1994: US05314408 (85 worldwide citation)

The present invention provides improvement usable with an intravascular catheter having a single common distal lumen with a reduced profile connected to two or more proximal lumens. The catheter will be loadable over a guidewire into a region of interest within a patient's vascular system. According ...


5
John R McKenzie: Flexible catheter drive cable. Cardiovascular Imaging Systems, Townsend and Townsend, April 28, 1992: US05108411 (81 worldwide citation)

A catheter comprises a flexible tubular member having a drive cable disposed in a lumen thereof. A work element is secured to a distal end of the lumen while a coupling member for rotating the cable secured to the proximal end thereof. The cable includes a more flexible end located within the distal ...


6
John R McKenzie, Stanley R Conston, David J Kupiecki: Injector for viscous materials. iScience Interventional Corporation, Weaver Austin Villeneuve & Sampson, June 28, 2011: US07967772 (73 worldwide citation)

An injector is provided to deliver microquantities of viscous materials into the body, such as the eye, for surgical purposes. The injector comprises a syringe body with a plunger disposed therein coupled to a positive displacement mechanism capable of progressively advancing the plunger to precisel ...


7
Stephen M Salmon, John R McKenzie, David A White: Tracking tip for a work element in a catheter system. Cardiovascular Imaging Systems, Townsend and Townsend and Crew, October 17, 1995: US05458585 (65 worldwide citation)

The claimed invention provides an improved tracking tip for use with a work element in a catheter system having a flexible tubular catheter body. Use of a tracking tip according to the present invention will facilitate advancement of the work element within the catheter body and will substantially e ...


8
John R McKenzie: Apparatus and method for the removal of moisture and mists from gas flows. April 4, 2006: US07022153 (30 worldwide citation)

Apparatus and method is provided for capturing centrifugally-liberated liquid from a gas stream including separator components installed in a cyclonic vessel. A plurality of concentric shells supported on a base form annular cavities arranged about a gas outlet for capturing separated liquids from a ...


9
Axel F Brisken, John R McKenzie, Robert F Zuk, Menahem Nassi, Mark W Cowan, Paul D Corl: Therapeutic ultrasound catheter for delivering a uniform energy dose. Pharmasonics, Townsend and Townsend and Crew, February 25, 2003: US06524271 (23 worldwide citation)

A method of treating a target region in a body lumen, said method comprising: directing a uniform dose of ultrasonic energy from an interior of the lumen radially outward over a treatment length of the lumen, wherein the dosage of ultrasonic energy received at any one point along the length varies b ...


10
John R McKenzie, Robert F Zuk, Axel F Brisken, Paul D Corl: Methods and kits for the inhibition of hyperplasia in vascular fistulas and grafts. Pharmasonics, Townsend and Townsend and Crew, May 14, 2002: US06387116 (12 worldwide citation)

A method for inhibiting hyperplasia at an anastomotic junction of a vascular fistula or vascular graft comprises exposing the anastomotic junction to vibrational energy at a mechanical index and for a time sufficient to inhibit hyperplasia. Kits are described comprising the catheter or a probe suita ...