1
Hongyan Guo, Darryl Kato, Thorsten A Kirschberg, Hongtao Liu, John O Link, Michael L Mitchell, Jay P Parrish, Jianyu Sun, James Taylor, Elizabeth M Bacon, Eda Canales, Aesop Cho, Choung U Kim, Jeromy J Cottell, Manoj C Desai, Randall L Halcomb, Scott E Lazerwith, Richard L Mackman, Hyung Jung Pyun, Joseph H Saugier, James D Trenkle, Winston C Tse, William J Watkins, Lianhong Xu: Antiviral compounds. Gilead Sciences, Viksnins Harris & Padys PLLP, January 3, 2012: US08088368 (39 worldwide citation)

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


2
Aesop Cho, Michael O Neil Hanrahan Clarke, Choung U Kim, John O Link, Hyung jung Pyun, Xiaoning C Sheng, Qiaoyin Wu: Antiviral compounds. Gilead Sciences, May 15, 2012: US08178491 (16 worldwide citation)

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


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Michael Graupe, John O Link, John W Patterson, Sheila Zipfel: Compounds and compositions as cathepsin S inhibitors. Axys Pharmaceuticals, Wayne W Montgomery, Rekha Bansal, December 10, 2002: US06492362 (11 worldwide citation)

The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.


5
John O Link, Arnold J Martelli, Valeri Martichonok, John W Patterson, Oliver L Saunders, Sheila Zipfel: Compounds and compositions as protease inhibitors. AXYS Pharmaceuticals, Townsend and Townsend and Crew, June 10, 2003: US06576630 (8 worldwide citation)

The present invention relates to novel alkanoyl-substituted heterocyclic derivatives which are cysteine protease inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.


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Hongyan Guo, Darryl Kato, Thorsten A Kirschberg, Evan S Krygowski, John O Link, Michael L Mitchell, Jay P Parrish, James Taylor: Antiviral compounds. Gilead Sciences, Sheppard Mullin Richter & Hampton, March 11, 2014: US08669234 (7 worldwide citation)

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


8
Elizabeth M Bacon, Jeromy J Cottell, Ashley Anne Katana, Darryl Kato, Evan S Krygowski, John O Link, James Taylor, Chinh Viet Tran, Teresa Alejandra Trejo Martin, Zheng Yu Yang, Sheila Zipfel: Antiviral compounds. Gilead Sciences, Sheppard Mullin Richter & Hampton, Lorna L Tanner, November 5, 2013: US08575135 (6 worldwide citation)

The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


9
Paula N Belloni, Donald R Hirschfeld, John O Link, John J Nestor Jr, Gary A Peltz: Cationic lipids for gene therapy. Syntex, Rohan Peries, March 7, 2000: US06034137 (5 worldwide citation)

This invention provides novel cationic lipids, particularly guanidino lipids, and methods for their preparation. Also provided are polyanionic-lipid complexes comprising the lipids of the invention, their preparation and use to deliver biologically active substances, particularly nucleic acids to ce ...


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Aesop Cho, Michael O Neil Hanrahan Clarke, Choung U Kim, John O Link, Hyung jung Pyun, Xiaoning C Sheng, Qiaoyin Wu: Antiviral compounds. Gilead Sciences, October 9, 2012: US08283442 (5 worldwide citation)

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.