1
Lynn Cook Winterton, Juergen Vogt, John Martin Lally, Friedrich Stockinger: Methods of modifying surface characteristics. Novartis, R Scott Meece, Robert Gorman, Richard I Gearhart, September 17, 2002: US06451871 (146 worldwide citation)

Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, followed by spray coating a polyanionic ...


2
Lynn Cook Winterton, Yongxing Qiu, John Martin Lally, Paul Clement Nicolson: Method for modifying a surface. Novartis, Jian S Zhou, R Scott Meece, April 13, 2004: US06719929 (91 worldwide citation)

A method of forming a contact lens within a mold is provided. A coating of a polyionic material(s) is applied to the mold before forming a lens therein. The coating can be applied by spraying or dipping the mold within a solution(s) of polyionic materials. Various other additives can also be applied ...


3
Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Yasuo Matsuzawa: Method for applying an LbL coating onto a medical device. Novartis, Jian Zhou, Robert Gorman, R Scott Meece, May 24, 2005: US06896926 (83 worldwide citation)

The present invention provides an improved LbL-coating process for modifying the surface of a medical device, preferably an ophthalmic device, more preferably a contact lens. An LbL coating on a contact lens, which is prepared according to the process of the invention, can have increased hydrophilic ...


4
Lynn Cook Winterton, Juergen Vogt, John Martin Lally, Friedrich Stockinger: Biomedical devices having improved surface characteristics. Novartis, Sheng Hsin Hu, Jian Zhou, Robert J Gorman, November 20, 2007: US07297725 (75 worldwide citation)

Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, followed by spray coating a polyanionic ...


5
Lynn Cook Winterton, Yongxing Qiu, John Martin Lally, Manal M Gabriel: Polymeric articles having a lubricious coating and method for making the same. Novartis, Jian Zhou, Robert Gorman, R Scott Meece, September 6, 2005: US06940580 (71 worldwide citation)

The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a lubricious coating including a capping layer of polyvinylpyrrolidone and/or at least one layer of a lubricious coating material and one layer of a polyionic material ha ...


6
Lynn Cook Winterton, John Martin Lally, Michael Rubner, Yongxing Qiu: Single-dip process for achieving a layer-by-layer-like coating. Novartis, Jian S Zhou, Robert J Gorman, R Scott Meece, September 21, 2004: US06793973 (64 worldwide citation)

A method of forming a coating of polyionic materials in a layer-by-layer-like manner onto a polymeric material is provided. A polymeric material, such as a contact lens, can be dipped once into a solution of polyionic materials such that layers of polyionic material can be formed thereon. A single d ...


7
Yongxing Qiu, Lynn Cook Winterton, John Martin Lally: LbL-coated medical device and method for making the same. Novartis, Jian S Zhou, Robert J Gorman, August 9, 2005: US06926965 (62 worldwide citation)

The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a core material and a biocompatible LbL coating non-covalently attached to said core material. The biocompatible LbL coating comprises at least one charge/non-charge bila ...


8
Celeste Aguado, Paul Clement Nicolson, Lynn Cook Winterton, Yongxing Qiu, John Martin Lally, Jacalyn Mary Schremmer: Polymeric materials for making contact lenses. Novartis, Jian Zhou, Robert Gorman, R Scott Meece, November 9, 2004: US06815074 (54 worldwide citation)

An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability be ...


9

10
Yongxing Qiu, Fiona Patricia Carney, Nichola Kotov, John Martin Lally, Carol Ann Morris, Lynn Cook Winterton: Diffusion-controllable coatings on medical device. Novartis, Jian S Zhou, R Scott Meece, Rob Gorman, December 7, 2004: US06827966 (47 worldwide citation)

The present invention provides a method for forming on a medical device, preferably an ophthalmic lens, more preferably a contact lens, a diffusion-controllable coating capable of controlling the out-diffusion or release of guest materials from the medical device. The method of the invention compris ...