1
Elizabeth A Wang, John M Wozney, Vicki Rosen: DNA sequences encoding osteoinductive products. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, May 7, 1991: US05013649 (253 worldwide citation)

Purified BMP-2 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.


2
John M Wozney, Vicki A Rosen, Elizabeth A Wang: DNA sequences encoding 5 proteins. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, April 21, 1992: US05106748 (166 worldwide citation)

Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.


3
Vicki A Rosen, Elizabeth A Wang, John M Wozney: DNA sequences encoding BMP-7 proteins. Ellen J Kapinos, Bruce M Eisen, August 25, 1992: US05141905 (158 worldwide citation)

Purified BMP-7 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartlage defects and in wound healing and related tissue repair.


4
Elizabeth A Wang, John M Wozney, Vicki Rosen: Osteoinductive factors. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, October 31, 1989: US04877864 (150 worldwide citation)

Human and bovine bone inductive factors are provided. Such factors may be produced by recombinant techniques and be useful in the treatment of bone defects.


5
John M Wozney, Elizabeth A Wang, Vicki A Rosen, Anthony J Celeste: DNA sequences encoding BMP-6 proteins. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, February 16, 1993: US05187076 (149 worldwide citation)

Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.


6
Elizabeth A Wang, John M Wozney, Vicki Rosen: DNA sequences encoding. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, May 26, 1992: US05116738 (136 worldwide citation)

Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.


7
Elizabeth A Wang, John M Wozney, Vicki Rosen: DNA sequences encoding BMP-1 products. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, April 28, 1992: US05108922 (105 worldwide citation)

Purified BMP-1 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.


8
Anthony J Celeste, John M Wozney, Vicki A Rosen, Neil M Wolfman, Gerald H Thomsen, Douglas A Melton: Methods of inducting formation of tendon and/or ligament tissue comprising administering BMP-12, BMP-13, and/or MP-52. Genetics Institute, President and Fellows of Harvard College, Steven R Lazar, Thomas J DesRosier, August 19, 1997: US05658882 (85 worldwide citation)

The present invention relates to methods for the induction of tendon/ligament-like tissue formation, wound healing and ligament and other tissue repair, using a composition comprising BMP-12, BMP-13 or MP-52, or combinations of the above.


9
Elizabeth A Wang, John M Wozney, Vicki A Rosen: DNA sequences encoding the osteoinductive proteins. Genetics Institute, Ellen J Kapinos, Bruce M Eisen, November 24, 1992: US05166058 (75 worldwide citation)

Purified BMP-2 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.


10
John M Wozney, Elizabeth A Wang, Vicki A Rosen: Methods for producing BMP-7 proteins. Genetics Institute, Ellen J Kapinos, Thomas J DesRosier, November 22, 1994: US05366875 (60 worldwide citation)

Purified BMP-7 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.