1
Michael A Boss, John H Kenten, John S Emtage, Clive R Wood: Multichain polypeptides or proteins and processes for their production. Celltech, Cushman Darby & Cushman, March 28, 1989: US04816397 (816 worldwide citation)

Multichain polypeptides or proteins and processes for their production in cells of host organisms which have been transformed by recombinant DNA techniques. According to a first aspect of the present invention, there is provided a process for producing a heterologous multichain polypeptide or protei ...


2
Jonathan K Leland, Haresh P Shah, John H Kenten, Jack E Goodman, George E Lowke, Yuzaburo Namba, Gary F Blackburn, Richard J Massey: Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets. Igen International, Eisai, Barry Evans Esq, David Rubin Esq, Curtis Morris & Safford P C, January 6, 1998: US05705402 (56 worldwide citation)

Disclosed and claimed are methods and apparatus for performing a binding assay for an analyte of interest present in a sample based upon measurement of electrochemiluminescence at an electrode. The method uses magnetically responsive particles. The method and apparatus call for a plurality of electr ...


3
Satyanarayana R Gudibande, John H Kenten: Electrochemiluminescent label for DNA probe assays. Igen, Curtis Morris & Safford, January 28, 1997: US05597910 (51 worldwide citation)

This invention relates to a new electrochemiluminescent (ECL) label for oligonucleotides using phosphoramidite chemistry.


4
John K Leland, Haresh P Shah, John H Kenten, Jack E Goodman, George E Lowke, Yuzaburo Namba, Gary F Blackburn, Richard J Massey: Methods and apparatus for improved luminescence assays. IGEN International, Whitman Breed Abbott & Morgan, December 4, 2001: US06325973 (46 worldwide citation)

An apparatus for performing a binding assay for an analyte of interest in a sample based upon measurement of clectrochemiluminescence at an electrode surface comprising: (a) a cell defining a sample; (b) an electrode adjacent a portion of the sample containing volume; (c) a voltage control device fo ...


5
John R Link, Satyanarayana R Gudibande, John H Kenten: Rapid assays for amplification products. IGEN, Curtis Morris & Safford P C, June 3, 1997: US05635347 (30 worldwide citation)

A method of detecting a nucleic acid sequence of interest in the amplification product of a polymerase chain reaction or other primer directed reaction comprising the steps of:


6
Richard O Williams, John H Kenten: Detecting water-borne parasites using electrochemiluminescence. IGEN International, Whitman Breed Abbott & Morgan, November 14, 2000: US06146838 (27 worldwide citation)

A method for the detection or quantitation of a water-borne parasite, such as Cryptosporidia. The detection or quantitation is accomplished by an electrochemiluminescence assay comprising the steps of filtering water to obtain a sludge thought to contain the parasite or a fragment thereof; extractin ...


7
John H Kenten, Jan Casadei, Michael J Powell: Luminescent chimeric proteins. IGEN International, Whitman Breed Abbott & Morgan, July 11, 2000: US06087476 (26 worldwide citation)

The invention relates to luminescent chimeric proteins which include a photoprotein and a second protein which may be light- or heavy-chain immunoglobulin, an antigenic peptide, avidin, streptavidin, or protein A. The invention also relates to chimeric protein genes, plasmids containing said gene, a ...


8
Rodger Smith, John McCafferty, David Chiswell, Michael J Darsley, Kevin Fitzgerald, John H Kenten, Mark T Martin, Richard C Titmas, Richard O Williams: Isolation and production of catalytic antibodies using phage technology. Whitman Breed Abbott & Morgan, January 5, 1999: US05855885 (26 worldwide citation)

Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodi ...


9
Richard J Massey, Jonathan K Leland, Haresh P Shah, John H Kenten, Jack E Goodman, George E Lowke, Yuzaburo Namba, Gary F Blackburn: Methods for improved particle electrochemiluminescence assay. IGEN International, Barry Evans Esq, John E Whitman Breed Abbott & Morgan Boyd Esq, August 10, 1999: US05935779 (23 worldwide citation)

The invention relates to methods of performing a binding assay for an analyte of interest present in a sample based upon electrochemiluminescence at an electrode of interest. Particles are employed in the method, which are then collected in a zone at which electrochemiluminescence can be induced, wh ...


10
John H Kenten, David M Simpson: Compounds and methods for the selective treatment of cancer and bacterial infections. Pro Neuron, Nixon & Vanderhye, April 17, 2001: US06218519 (22 worldwide citation)

The present invention relates to compounds containing an anthracyclinone group such as doxorubicin, daunorubicin or a derivative thereof. The compounds of the invention also contain ester, glycoside or glucuronide structures which are hydrolyzed by the corresponding esterase, glycosidase or glucuron ...