1
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Integrated tissue heating and cooling apparatus. Curon Medical, Ryan Kromholz & Manion S C, August 14, 2001: US06273886 (489 worldwide citation)

Systems and methods integrate the control of an energy generator, to supply energy to an electrode structure to heat a tissue region, and the control of a pumping mechanism, to supply cooling fluid to control tissue temperature in the region.


2
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions. Curon Medical, Ryan Kromholz & Manion SC, July 10, 2001: US06258087 (465 worldwide citation)

Expandable assemblies for treating a tissue region at or near a sphincter comprises a support basket formed from an array of spines. A mechanism flexes the spines to expand and collapse the basket. Electrodes carried by the spines for advancement in a path to penetrate the tissue region upon expansi ...


3
Stuart D Edwards, John Gaiser, David S Utley: Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors. Curon Medical, Ryan Kromholz & Manion S C, June 18, 2002: US06405732 (413 worldwide citation)

A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the ...


4
Michel Haissaguerre, Walter Bruszewski, Le Le, Mark Maguire, John Gaiser, Huu Nguyen: System and methods for tissue mapping and ablation. Medtronic, Daniel W Latham, Harold R Patton, May 30, 2000: US06068629 (389 worldwide citation)

A steerable electrophysiology catheter includes a shaft having a distal ablation segment with one or more electrodes coupled to a source of electrical energy by a connector extending through the shaft. The distal ablation segment of the shaft is movable between a collapsed configuration sized for pe ...


5
David Utley, Scott West, John Gaiser, Rachel Croft: Systems and methods for treating dysfunctions in the intestines and rectum. Curon Medical, Ryan Kromholz & Manion S C, November 11, 2003: US06645201 (286 worldwide citation)

A sphincter tissue region is treated using a support structure sized for advancement into the anal canal. At least one electrode is carried by the structure. A mechanism is coupled to the electrode to move the electrode between a first position retracted in the support structure and a second positio ...


6
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Graphical user interface for association with an electrode structure deployed in contact with a tissue region. Curon Medical, Ryan Kromholz & Manion S C, March 19, 2002: US06358245 (269 worldwide citation)

Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the elect ...


7
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin, Ronald Lax: Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions. Curon Medical, Ryan Kromholz & Manion S C, December 4, 2001: US06325798 (268 worldwide citation)

Systems and methods treat a tissue region at or near a sphincter by deploying a carrier, which carries an electrode that can be advanced to penetrate tissue. Negative pressure is applied through a suction port on the carrier near the electrode, to draw tissue in the tissue region inward against the ...


8
Michel Haissaguerre, Walter Bruszewski, Le Le, Mark Maguire, John Gaiser, Huu Nguyen: Systems and methods for tissue mapping and ablation. Medtronic, Townsend and Townsend and Crew, June 29, 1999: US05916213 (252 worldwide citation)

A steerable electrophysiology catheter includes a shaft having a distal ablation segment with one or more electrodes coupled to a source of electrical energy by a connector extending through the shaft. The distal ablation segment of the shaft is movable between a collapsed configuration sized for pe ...


9
Stuart D Edwards, John Gaiser, David S Utley, Scott West, Jay Qin: Electrodes for creating lesions in tissue regions at or near a sphincter. Curon Medical, Ryan Kromholz & Manion S C, May 13, 2003: US06562034 (214 worldwide citation)

Improved electrode assemblies for treating a tissue region at or near a sphincter comprise a support structure and an electrode carried by the support structure for advancement in a path to penetrate the tissue region. In one arrangement, the electrode has a non-cylindrical cross section selected to ...


10
David Utley, Scott West, John Gaiser, Rachel Croft: Mederi Therapeutics, Ryan Kromholz & Manion S C, April 20, 2010: US07699844 (201 worldwide citation)

A sphincter tissue region is treated using a support structure sized for advancement into the anal canal. At least one electrode is carried by the structure. A mechanism is coupled to the electrode to move the electrode between a first position retracted in the support structure and a second positio ...