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Natesan Murugesan, John E Tellew, John E Macor, Zhengxiang Gu: Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists. Bristol Myers Squibb Company, Henry H Gu, Stephen B Davis, February 8, 2005: US06852745 (40 worldwide citation)

Novel biphenyl sulfonamide compounds which are combined angiotensin and endothelin receptor antagonists are claimed along with methods of using such compounds in the treatment of conditions such as hypertension and other diseases, as well as pharmaceutical compositions containing such compounds.


2
Harry R Howard, John E Macor, Bertrand L Chenard, Jeffrey S Sprouse, David W Schulz: Compositions containing sertraline and a 5-HT.sub.1D receptor agonist or antagonist. Pfizer, Peter C Richardson, Paul H Ginsburg, Garth Butterfield, January 28, 1997: US05597826 (39 worldwide citation)

The present invention relates to novel compositions containing the serotonin selective re-uptake inhibitor (SSRI), preferably (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenam ine, and an agonist or antagonist of the serotonin 1 (5-HT.sub.1) receptor and to the use of such c ...


3
John E Macor: Pharmaceutically active 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines. Pfizer, Peter C Richardson, Paul H Ginsburg, Karen DeBenedictis, September 24, 1991: US05051412 (39 worldwide citation)

Compounds of the formula ##STR1## wherein one of A, B, D and E is N and the remaining three atoms are C; R.sup.1 and R.sup.2 are independently selected from hydrogen and C.sub.1 to C.sub.6 alkyl; and R.sup.3, R.sup.4, R.sup.5 and R.sub.6 are independently selected from hydrogen, halogen, hydroxy, C. ...


4
John E Macor, Martin J Wythes: Indole derivatives. Pfizer, Peter C Richardson, Paul H Ginsburg, Grover F Fuller Jr, August 13, 1996: US05545644 (29 worldwide citation)

Compounds of the formula ##STR1## wherein n is 0, 1, or 2; X is hydrogen, chlorine, bromine or iodine; R.sub.1 is hydrogen; R.sub.3 is selected from hydrogen and C.sub.1 to C.sub.6 linear or branched alkyl; and R.sub.2 is as defined in the specification and the pharmaceutically acceptable salts ther ...


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John E Macor, David P Rotella, Harold N Weller III, David W Cushman, Joseph P Yevich: Quinazolinone inhibitors of cGMP phosphodiesterase. Bristol Myers Squibb Company, Stephen B Davis, Suzanne Babajko, July 11, 2000: US06087368 (22 worldwide citation)

Novel quinazolinone compounds, methods of using such compounds in the treatment of cGMP-associated conditions such as erectile dysfunction, and pharmaceutical compositions containing such compounds.


7
Michael F Parker, Katharin E McElhone, Robert A Mate, Joanne J Bronson, Yonghua Gai, Carl P Bergstrom, Lawrence R Marcin, John E Macor: α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors. Bristol Myers Squibb Company, Aldo A Algieri, November 27, 2007: US07300936 (21 worldwide citation)

There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid ac ...


8
John E Macor, Martin J Wythes: Indole derivatives. Pfizer, Peter C Richardson, Paul H Ginsburg, Grover F Fuller Jr, November 26, 1996: US05578612 (20 worldwide citation)

Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, X and n are as defined in the claims and the pharmaceutically acceptable salts thereof are new. These compounds are useful psychotherapeutics and are potent serotonin (5-HT.sub.1) agonists and may be used in the treatment of depres ...


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John E Macor, Martin J Wythes: Indole derivatives. Pfizer, Peter C Richardson, Paul H Ginsburg, Grover F Fuller Jr, March 4, 1997: US05607951 (16 worldwide citation)

Compounds of the formula ##STR1## wherein the substituents are as defined in the description and the pharmaceutically acceptable salts thereof are new. These compounds are useful psychotherapeutics and are potent serotonin (5-HT.sub.1) agonists and may be used in the treatment of depression, anxiety ...