1
John B Simpson, Edward W Robert: Vascular guiding catheter assembly and vascular dilating catheter assembly and a combination thereof and methods of making the same. Advanced Catheter Systems, April 6, 1982: US04323071 (464 worldwide citation)

A combination guiding catheter assembly and a dilating catheter assembly. The guiding catheter assembly includes a first flexible tubular member formed of a material which has a low coefficient of friction and a second flexible tubular member encasing said first tubular member so that the first tubu ...


2
Hanson S Gifford III, John B Simpson, Peter S Brown: Atherectomy device for severe occlusions. Devices for Vascular Intervention, Townsend & Townsend, May 22, 1990: US04926858 (455 worldwide citation)

An atherectomy catheter for removal of plaque buildup from the walls of a blood vessel. The atherectomy catheter includes a cutter assembly disposed at the distal end of a flexible guide tube that may be inserted into a vessel and directed to the occlusion. A proximal actuator assembly is adapted to ...


3
John B Simpson, Hira Thapliyal, Hanson S Gifford III, Tommy G Davis: Atherectomy device having a flexible housing. Devices for Vascular Intervention, Flehr Hohbach Test Albritton & Herbert, November 1, 1988: US04781186 (334 worldwide citation)

An atherectomy device having a housing at the distal end of a catheter adapted for insertion into the vascular system. The housing has a cutout in one side, and a cutter that is mounted in the housing for both axial and rotary movement with respect to the cutout. At least a portion of the housing is ...


4
Hanson S Gifford III, John B Simpson: Single lumen atherectomy catheter device. Devices for Vascular Intervention, Flehr Hohbach Test Albritton & Herbert, June 2, 1987: US04669469 (315 worldwide citation)

Atherectomy device for removing material from an atheroma in the vascular system. A cutter is mounted in a cylindrical housing having a cutout on one side thereof at the distal end of a catheter. The catheter has a single luminal opening, and a flexible drive cable for operating the cutter passes th ...


5
John B Simpson, Scott C Anderson: Adjustable treatment chamber catheter. Technology Development Center, Douglas A Chaikin, October 31, 1995: US05462529 (295 worldwide citation)

Disclosed herein is a catheter device for treatment of disease in biological conduits. The device has inner and outer coaxial catheter members, each having an inflatable balloon attached near its distal end. When the balloons are inflated, a sealed treatment chamber is created between the balloons. ...


6
John B Simpson, Richard L Mueller, Peter S Brown, James R Kermode: Atherectomy device and method. Devices for Vascular Intervention, Townsend and Townsend, September 10, 1991: US05047040 (263 worldwide citation)

An atherectomy device for removing stenosis materials from a vascular vessel is provided. The atherectomy device includes a flexible tubular member, a flexible drive means disposed within the tubular member, and a cutting assembly carried by the distal extremity of the tubular member. The cutting as ...


7
John B Simpson, Hanson S Gifford III, Kenneth A Stenstrom: Motor drive unit. Devices for Vascular Intervention, Flehr Hohbach Test Albritton & Herbert, September 20, 1988: US04771774 (235 worldwide citation)

Motor drive unit for use with an atherectomy device having a flexible drive cable and a finger operated member for advancing and retracting the drive cable. The drive unit comprises a motor and a power supply mounted in a case of a size which fits comfortably in a human hand, with a power switch pos ...


8
Richard L Mueller, Tommy G Davis, Peter S Brown, John B Simpson: Catheter and method for making intravascular incisions. Devices for Vascular Intervention, Townsend and Townsend, October 1, 1991: US05053044 (225 worldwide citation)

A vascular catheter includes a blade tip at its distal end. In the specific embodiments, a blade is mounted within the blade tip and a mechanism provided for extending the blade transversely when the blade tip is located within a region of stenosis. By extending the blade and axially translating the ...


9
John B Simpson: Atherectomy device and method. December 25, 1990: US04979951 (216 worldwide citation)

Atherectomy device having a generally cylindrical housing formed of a relatively rigid material. The housing has rounded distal and proximal end portions. The housing is formed with a cutout extending longitudinally of the housing on one side of the housing. An atheroma cutter is disposed to the pro ...


10
John B Simpson, Scott C Anderson, John J Frantzen, Peter S Brown, James M Cannon Jr, Geoffrey A Orth: Bi-axial cutter apparatus for catheter. Technology Development Center, Douglas A Chaikin, August 15, 1995: US05441510 (196 worldwide citation)

An cutter apparatus for removing obstructive tissue has a distal housing having a window for invaginating tissue. An axially reciprocating and rotating cutting blade makes successive longitudinal cuts while slowly rotating across the open window. An axial guide assembly holds the cutting edge of the ...