1
Joachim Hoenes, Jurgen Schaeffler: Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, February 15, 1994: US05286362 (484 worldwide citation)

The subject matter of the invention is a method for the electrochemical determination of an analyte in the presence of an oxidoreductase and a reducible substance which transfers electrons which arise during the course of the determination reaction from the oxidoreductase onto an electrode and thus ...


2
Joachim Hoenes, Jurgen Schaeffler: Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, June 16, 1992: US05122244 (235 worldwide citation)

The subject matter of the invention is a method for the electrochemical determination of an analyte in the presence of an oxidoreductase and a reducible substance which transfers electrons which arise during the course of the determination reaction from the oxidoreductase onto an electrode and thus ...


3
Joachim Hoenes: Colorimetric assay by enzymatic oxidation in the presence of an aromatic nitroso or oxime compound. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, April 27, 1993: US05206147 (88 worldwide citation)

The present invention provides a process for the colorimetric determination of an analyte by means of enzymatic oxidation of the analyte in the presence of an electron acceptor and determination of the reduced electron acceptor by color formation as measure for the amount of the analyte, wherein the ...


4
Joachim Hoenes: Portable measuring system having a moisture-proof assembly space. Roche Diagnostics Operations, Bose McKinney & Evans, July 31, 2012: US08231548 (48 worldwide citation)

A portable measuring system which analyzes a liquid sample for at least one analyte. The portable measuring system has a substantially moisture-proof housing with an internal atmosphere. The housing prevents moisture from the air and water vapor from penetrating into the housing. The portable measur ...


5
Joachim Hoenes: Process and agent for the colorimetric determination of an analyte by means of enzymatic oxidation. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, August 2, 1994: US05334508 (35 worldwide citation)

The present invention provides a process for the colorimetric determination of an analyte by means of enzymatic oxidation of the analyte in the presence of an electron acceptor and determination of the reduced electron acceptor by color formation as measure for the amount of the analyte, wherein the ...


6
Joachim Hoenes: Method for the colorimetric determination of an analyte by means of benzyl alcohol dehydrogenase and a chromogenic redox indicator. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, August 29, 1995: US05445943 (35 worldwide citation)

The invention concerns a method for the colorimetric determination of NADH by means of enzymatic oxidation with benzyl alcohol dehydrogenase whereby an aromatic nitrosoaniline compound of the general formula I is reduced to a colored quinone diimine ##STR1## in which R.sup.1 denotes hydrogen, haloge ...


7
Dieter Heindl, Joachim Hoenes, Carina Horn, Piet Herdewijn: Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH. Roche Diagnostics Operations, Justin L Sage, Roche Diagnostics Operations, June 30, 2009: US07553615 (21 worldwide citation)

The invention concerns stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives, enzyme complexes of these derivatives and their use in biochemical detection methods and reagent matrices.


8
Joachim Hoenes, Hans Wielinger, Volker Unkrig: Use of a sparingly soluble salt of a heteropoly acid for the determination of an analyte, a corresponding method of determination as a suitable agent therefor. Boehringer Mannehim, Nikaido Marmelstein Murray & Oram, August 31, 1993: US05240860 (20 worldwide citation)

A sparingly soluble salt of a heteropoly acid is used for the determination of an analyte which is an aromatic amine rich in electrons or together with another substance leads to such an amine. The analyte is determined by means of the heteropoly blue color formed.


9
Joachim Hoenes, Volker Unkrig: Method for the colorimetric determination of an analyte with a PQQ-dependent dehydrogenase. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, January 16, 1996: US05484708 (16 worldwide citation)

The invention concerns a method for the colorimetric determination of an analyte by means of enzymatic oxidation with a PQQ-dependent dehydrogenase in the presence of an electron acceptor from the group of the electron-rich aromatic nitroso compounds by enzymatic reduction of the nitroso compound to ...


10
Joachim Hoenes, Hans Wielinger, Volker Unkrig: Use of sparingly soluble salt of a heteropoly acid for the determination of an analyte, a corresponding method of determination as well as a suitable agent thereof. Boehringer Mannheim, Nikaido Marmelstein Murray & Oram, January 17, 1995: US05382523 (16 worldwide citation)

A sparingly soluble salt of a heteropoly acid is used for the determination of an analyte which is an aromatic amine rich in electrons or together with another substance leads to such an amine. The analyte is determined by means of the heteropoly blue color formed.