1
James E Shapland, Mark B Knudson, Jin Shimada: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 15, 1994: US05286254 (551 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


2
J Edward Shapland, Keith R Hildelbrand, Joel R Racchini, Jin Shimada, Mark B Knudson: Polymer matrix drug delivery apparatus. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt P A, September 15, 1998: US05807306 (435 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue using a catheter device including a polymer matrix containing a drug. The drug is actively transported from the polymer matrix to the internal body tissue using iontophoresis or phonophoresis. In addition, the ...


3
James E Shapland, Mark B Knudson, Jin Shimada: Phoretic balloon catheter with hydrogel coating. Cortrak Medical, Moore & Hansen, May 13, 1997: US05628730 (390 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


4
James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 1, 1994: US05282785 (283 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


5
Joel R Racchini, James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Porous balloon for selective dilatation and drug delivery. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, October 17, 1995: US05458568 (273 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing t ...


6
James E Shapland, Mark B Knudson, Jin Shimada, Joel R Racchini: Simultaneous angioplasty and phoretic drug delivery. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, March 12, 1996: US05498238 (185 worldwide citation)

A method of simultaneous angioplasty and drug delivery to a localized portion of coronary or peripheral arteries or any other type of body passage that has a stricture. The invention contemplates positioning a drug delivery device in a body passageway and then selectively introducing a selected drug ...


7
Jin Shimada, James E Shapland: Drug delivery by multiple frequency phonophoresis. Trancell, Merchant Gould Smith Edell Welter & Schmidt, December 7, 1993: US05267985 (165 worldwide citation)

The present invention provides a method and apparatus for enhancing the diffusion of a substance to a local area of material or tissue by providing ultrasonic energy to the substance and material in two or more distinct frequencies simultaneously. Each of the distinct frequencies of ultrasonic energ ...


8
Jin Shimada: Process for producing steerable sheath catheters. Biotran Corporation, Kinney & Lange P A, June 24, 2003: US06582536 (64 worldwide citation)

The invention is a method for manufacturing a steerable catheter having a distal end, proximal end, an outer jacket, a pull wire and a central lumen. The central lumen is maintained in a circular shape without bulges diminishing the useful inter-diameter by using an outer jacket with an elliptical s ...


9
Tomasz J Petelenz, Stephen C Jacobsen, Robert L Stephen, Jon Beck, Jin Shimada: Hydratable bioelectrode. Iomed, Hana Dolezalova, February 11, 1992: US05087242 (48 worldwide citation)

A hydratable iontophoretic bioelectrode includes a layer of material for absorbing and holding an ionized fluid when placed in contact with the fluid. A conductive sheet of material is positioned in contact with one side of the layer of material and is connectable to an electrical charged source to ...


10
Jin Shimada: Steerable sheath catheters. Biotran Corporation, Kinney & Lange P A, December 27, 2005: US06979312 (28 worldwide citation)

The invention is a steerable catheter having a pull wire, a central lumen and a control handle. The central lumen is maintained in a circular shape without obstructions diminishing the useful inter-diameter. The pull wire friction is also reduced by using one wire of larger diameter to create the lu ...



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