1
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Jones & Askew, July 18, 2000: US06090925 (165 worldwide citation)

Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of homogeneously distributed, intertwined macromol ...


2
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard, Frank J Riske: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Jones & Askew, November 9, 1999: US05981719 (145 worldwide citation)

Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of homogeneously distributed, intertwined macromol ...


3
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard, Frank J Riske: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Wolf Greenfield & Sacks P C, July 31, 2001: US06268053 (114 worldwide citation)

Methods relating to the field of biochemistry and more specifically relating to microparticles for use in diagnostics, therapeutics, and research are provided.


4
James E Woiszwillo, Jie Di: Method and kit for making a polysaccharide-protein conjugate. Middlesex Sciences, Jones & Askew, September 10, 1996: US05554730 (53 worldwide citation)

A method and kit for making a polysaccharide-protein Schiff base conjugate. A polysaccharide is oxidized with an oxidizing agent and combined with a protein in the presence of a macromolecular crowding agent to form a Schiff base. Preferably, the macromolecular crowding agent is a soluble linear pol ...


5
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Jones Askew, December 15, 1998: US05849884 (7 worldwide citation)

Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of homogeneously distributed, intertwined macromol ...


6
David Heilman, Jie Di, Brian Bray: Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy. Trimeris, M Bud Nelson, May 16, 2006: US07045552 (3 worldwide citation)

Provided is a pharmaceutical composition comprising a solution comprised of synthetic peptide in a final concentration of not less than 70 mg/ml in admixture with a polyol; wherein the synthetic peptide is an HIV fusion inhibitor, and wherein the polyol is in a final concentration of no less than 5 ...


7
David Heilman, Jie Di, Brian Bray: Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy. M Bud Nelson, Trimeris, April 1, 2004: US20040063637-A1

Provided is a pharmaceutical composition comprising a solution comprised of synthetic peptide in a final concentration of not less than 70 mg/ml in admixture with a polyol; wherein the synthetic peptide is an HIV fusion inhibitor, and wherein the polyol is in a final concentration of no less than 5 ...


8
Brian Bray, Jie Di, David Heilman, Peter Silinski, Scott Webb: Novel formulations for delivery of antiviral peptide therapeutics. Jones Day, March 12, 2009: US20090068243-A1

Provided herein are compositions and methods for their administration as therapeutic agents. In particular, provided herein are compositions and their use for the administration of antiviral peptide therapeutics.