1
Sun Lijun, Borella Christopher, Li Hao, Jiang Jun, Chen Shoujun, Koya Keizo, Inoue Takayo, Du Zhenjian, Foley Kevin, Wu Yaming, Zhang Mei, Ying Weiwen: Isoxazole combretastin derivatives for the treatment of disorders. Synta Pharmaceuticals, Sun Lijun, Borella Christopher, Li Hao, Jiang Jun, Chen Shoujun, Koya Keizo, Inoue Takayo, Du Zhenjian, Foley Kevin, Wu Yaming, Zhang Mei, Ying Weiwen, DAVIS Steven G, August 24, 2006: WO/2006/089177 (40 worldwide citation)

The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative ...


2
Xie Yu, Holmqvist Mats, Mahiou Jerome, Ono Mitsunori, Sun Lijun, Chen Shoujun, Zhang Shijie, Jiang Jun, Chimmanamada Dinesh, Fleig Andrea, Yu Chih Yi: Method for modulating calcium ion-release-activated calcium ion channels. Synta Pharmaceuticals, Xie Yu, Holmqvist Mats, Mahiou Jerome, Ono Mitsunori, Sun Lijun, Chen Shoujun, Zhang Shijie, Jiang Jun, Chimmanamada Dinesh, Fleig Andrea, Yu Chih Yi, HSI Jeffrey D, February 3, 2005: WO/2005/009954 (28 worldwide citation)

The invention relates to a method for modulating Ca 2'-release-activated Ca 2+ channels (CRAG) in a cell by administering to the cell a compound of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein.


3
Jiang Jun, Zhang Junyi, Vo Nha Huu, Chen Shoujun: Phenyl and pyridyl compounds for inflammation and immune-related uses. Synta Pharmaceuticals, Jiang Jun, Zhang Junyi, Vo Nha Huu, Chen Shoujun, HSI Jeffrey D, August 2, 2007: WO/2007/087429 (28 worldwide citation)

The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R1, X1, X2, Y, Z, L, and n are defined herein. The compounds are useful as immunosuppressive agents and for treating and preventing inflammatory condit ...


4
Sun Lijun, Chen Shoujun, Jiang Jun, Xie Yu, Yu Chih Yi: Compounds for inflammation and immune-related uses. Synta Pharmaceuticals, Sun Lijun, Chen Shoujun, Jiang Jun, Xie Yu, Yu Chih Yi, HSI Jeffrey D, August 3, 2006: WO/2006/081391 (27 worldwide citation)

The invention relates to compounds of structural formula (I) and structural formula (Vl): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R, R1, R2, Z, L, and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and prev ...


5
Sun Lijun, Chen Shoujun, Jiang Jun, Xia Zhi Qiang, Xie Yu, Yu Chih Yi: Thiophene compounds for inflammation and immune-related uses. Synta Pharmaceuticals, Sun Lijun, Chen Shoujun, Jiang Jun, Xia Zhi Qiang, Xie Yu, Yu Chih Yi, HSI Jeffrey D, August 3, 2006: WO/2006/081389 (23 worldwide citation)

The invention relates to compounds of structural formulas (I) and (XVI) or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X1, X2, Z, L, L2, R1, R2, R3, R21, n, q, and t are defined herein. These compounds are useful as immunosuppressive agents and for treating an ...


6
Sun Lijun, Chen Shoujun, Xia Zhi Qiang, Jiang Jun, Xie Yu, Zhang Junyi: Compounds for inflammation and immune-related uses. Synta Pharmaceuticals, Sun Lijun, Chen Shoujun, Xia Zhi Qiang, Jiang Jun, Xie Yu, Zhang Junyi, HSI Jeffrey D, August 10, 2006: WO/2006/083477 (23 worldwide citation)

The invention relates to compounds of structural formulas (I), (VII) and (Xl): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein XI, X2, X3. Y, Z, L, R1, R2, R3, R18 and n are defined herein. These compounds are useful as immunosuppressive agents and for treating ...


7
Chen Shoujun, Jiang Jun, Zhang Junyi, Xie Yu: Benzoimidazolyl-parazine compounds for inflammation and immune-related uses. Synta Pharmaceuticals, Chen Shoujun, Jiang Jun, Zhang Junyi, Xie Yu, HSI Jeffrey D, September 27, 2007: WO/2007/109362 (20 worldwide citation)

The invention relates to compounds of structural formula (I) or (III) or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein ring A, X1, X2, X3, X5, R1, R4, Y, Z, L, m and n are defined herein. These compounds are useful as immunosuppressive agents and for treating an ...


8
Xie Yu, Holmqvist Mats, Mahiou Jerome, Ono Mitsunori, Sun Lijun, Chen Shoujun, Zhang Shijie, Jiang Jun, Chimmanamada Dinesh, Yu Chih Yi: Compounds for inflammation and immune-related uses. Synta Pharmaceuticals, Xie Yu, Holmqvist Mats, Mahiou Jerome, Ono Mitsunori, Sun Lijun, Chen Shoujun, Zhang Shijie, Jiang Jun, Chimmanamada Dinesh, Yu Chih Yi, HSI Jeffrey D, February 3, 2005: WO/2005/009539 (20 worldwide citation)

The invention relates to compounds of formula (I) or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune di ...


9
Chen Shoujun, Jiang Jun, Li Hao, James David, Chimmanamada Dinesh, Borella Christopher, Sun Lijun, Xie Yu, Holmqvist Mats, Mahiou Jerome, Xia Zhi Qiang: Compounds for inflammation and immune-related uses. Synta Pharmaceutical, Chen Shoujun, Jiang Jun, Li Hao, James David, Chimmanamada Dinesh, Borella Christopher, Sun Lijun, Xie Yu, Holmqvist Mats, Mahiou Jerome, Xia Zhi Qiang, HSI Jeffrey D, March 30, 2006: WO/2006/034402 (19 worldwide citation)

The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune d ...


10
Sun Lijun, Jiang Jun: Compounds for treating proliferative disorders. Synta Pharmaceuticals, Sun Lijun, Jiang Jun, DAVIS Steven G, February 12, 2009: WO/2009/020631 (15 worldwide citation)

Disclosed are compounds and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer induction. Also, disclosed are pharmaceutical compositions comprising c ...