1

2
Stephen G Hoge, Antonin de Fougerolles, Jeff Lynn Ellsworth: Compositions and methods of altering cholesterol levels. Moderna Therapeutics, DT Ward PC, Donna T Ward, Jennifer F Bryan, March 17, 2015: US08980864 (9 worldwide citation)

The present invention relates to compositions, methods and kits using polynucleotides, primary transcripts and mmRNA molecules.


3

4

5

6
Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Sayda M Elbashir, Matthias John, Atanu Roy, Susan Whoriskey, Kristy M Wood, Paul Hatala, Jason P Schrum, Kenechi Ejebe, Jeff Lynn Ellsworth, Justin Guild: Modified polynucleotides for the production of oncology-related proteins and peptides. ModernaTX, Clark & Elbing, March 7, 2017: US09587003

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.


7
Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Sayda M Elbashir, Matthias John, Atanu Roy, Susan Whoriskey, Kristy M Wood, Paul Hatala, Jason P Schrum, Kenechi Ejebe, Jeff Lynn Ellsworth, Justin Guild: In vivo production of proteins. Moderna Therapeutics, DT Ward PC, Donna T Ward, Jennifer F Bryan, December 29, 2015: US09221891

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.