1
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Integrated tissue heating and cooling apparatus. Curon Medical, Ryan Kromholz & Manion S C, August 14, 2001: US06273886 (489 worldwide citation)

Systems and methods integrate the control of an energy generator, to supply energy to an electrode structure to heat a tissue region, and the control of a pumping mechanism, to supply cooling fluid to control tissue temperature in the region.


2
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions. Curon Medical, Ryan Kromholz & Manion SC, July 10, 2001: US06258087 (465 worldwide citation)

Expandable assemblies for treating a tissue region at or near a sphincter comprises a support basket formed from an array of spines. A mechanism flexes the spines to expand and collapse the basket. Electrodes carried by the spines for advancement in a path to penetrate the tissue region upon expansi ...


3
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Graphical user interface for association with an electrode structure deployed in contact with a tissue region. Curon Medical, Ryan Kromholz & Manion S C, March 19, 2002: US06358245 (269 worldwide citation)

Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the elect ...


4
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin, Ronald Lax: Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions. Curon Medical, Ryan Kromholz & Manion S C, December 4, 2001: US06325798 (268 worldwide citation)

Systems and methods treat a tissue region at or near a sphincter by deploying a carrier, which carries an electrode that can be advanced to penetrate tissue. Negative pressure is applied through a suction port on the carrier near the electrode, to draw tissue in the tissue region inward against the ...


5
Stuart Edwards, John Gaiser, David S Utley, Scott West, Jay Chin: Stomach and adjoining tissue regions in the esophagus. Curon Medical, Ryan Kromholz & Manion S C, October 15, 2002: US06464697 (173 worldwide citation)

Systems and methods treat a tissue region. In one arrangement, the systems and methods deploy an electrode on a support structure in a tissue region at or near the cardia of the stomach. The support structure has a proximal region and a distal region. The proximal region is enlarged in comparison to ...


6
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Actively cooled electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions. Curon Medical, Ryan Kromholz & Manion S C, August 27, 2002: US06440128 (107 worldwide citation)

An assembly for treating tissue at or near the sphincter includes a support structure for deployment in a tissue region, and a an electrode carried by the support structure. The support structure includes a spine with a lumen having an exit port, the electrode being deployable from the exit port. Th ...


7
Stuart Edwards, John Gaiser, David S Utley, Scott West, Jay Chin: Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions. Ryan Kromholz & Msnion Sc, January 31, 2002: US20020013581-A1

Systems and methods manipulate a support structure to form a composite lesion in a tissue region at or near a sphincter. The support structure carries an array of electrodes attachable to a source of energy capable of heating tissue when transmitted by the electrodes. The systems and methods advance ...


8
Stuart Edwards, John Gaiser, David Utley, Scott West, Jay Chin: Actively cooled electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions. Ryan Kromholz & Manion Sc, June 13, 2002: US20020072738-A1

Electrode assemblies actively cool mucosal surface tissue at or near a sphincter while applying energy through an electrode to ohmically heat tissue beneath the surface. The applied energy creates one or more lesions, or a prescribed pattern of lesions, below the mucosal surface. Natural healing of ...