1
James V Bacus, James W Bacus: Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope. Bacus Research Laboratories, Fitch Even Tabin & Flannery, August 8, 2000: US06101265 (211 worldwide citation)

An apparatus and method acquires and stores multiple resolution images from a specimen on a support and provides to the user a low magnification, reconstructed macro image of the entire specimen, or a large portion thereof, to aid the person in selecting points of interest to be viewed or analyzed a ...


2
James V Bacus, James W Bacus: Method and apparatus for creating a virtual microscope slide. Bacus Research Laboratories, Fitch Even Tabin & Flannery, August 7, 2001: US06272235 (208 worldwide citation)

A method and apparatus are disclosed for constructing a virtual microscope slide comprised of digitally scanned images from a microscope specimen. The digitally scanned images are arranged in a tiled format convenient for viewing without a microscope, and for transferring the tiled images for viewin ...


3
James W Bacus, James V Bacus: Method and apparatus for internet, intranet, and local viewing of virtual microscope slides. Bacus Research Laboratories, Fitch Even Tabin & Flannery, May 28, 2002: US06396941 (193 worldwide citation)

A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method an ...


4
James W Bacus, James V Bacus, Robert E Wagner: Method and apparatus for automated assay of biological specimens. Becton Dickinson and Company, Allen W Wark, June 27, 1995: US05428690 (163 worldwide citation)

An apparatus and method for automated assay of biological specimens positioned on microscope slides. The apparatus comprises an interactive optical subsystem for viewing the biological specimen on the slide and for producing an interactive video signal corresponding to the viewed image. An automated ...


5
James W Bacus: Methods and apparatus for the quantitation of nuclear protein. Cell Analysis Systems, Fitch Even Tabin & Flannery, April 13, 1993: US05202931 (138 worldwide citation)

An image analysis system is used for the quantitation of nuclear proteins in cell populations. Particularly, the hormonal receptor content of fine needle aspirates of human breast carcinomas are evaluated. Estrogen or progesterone receptors are amplified and visualized in the specimen by a staining ...


6
James W Bacus: Method of and an apparatus for image analyses of biological specimens. Cell Analysis Systems, Fitch Even Tabin & Flannery, April 26, 1988: US04741043 (117 worldwide citation)

A user interactive system for dynamically testing and evaluating various cells, antigens, or other materials taken from the human body. More specifically, the DNA in specimen cells is analyzed and quantified by image analysis using pattern recognition techniques. The user is provided with a unique s ...


7
James W Bacus: Dual resolution method and apparatus for use in automated classification of pap smear and other samples. Rush Presbyterian St Luke s Medical Center, Fitch Even & Tabin, November 27, 1979: US04175860 (111 worldwide citation)

A method and apparatus is disclosed for use in performing automated classification of cells of a pap smear as well as other types of cells, such as red blood cells and blood cell neutrophiles. The apparatus generates an image that is split into two paths, (1) a high resolution image of primarily the ...


8
James W Bacus: Method of and an apparatus for automatic classification of red blood cells. Rush Presbyterian St Luke s Medical Center, Fitch Even Tabin & Luedeka, June 27, 1978: US04097845 (100 worldwide citation)

A method and apparatus for automatically classifying abnormal and normal red blood cells is disclosed. The abnormal cells may be differentiated into mutually exclusive subpopulations. The individual hemoglobin characteristic for each red blood cell is measured and a hemoglobin parameter may be repor ...


9
James V Bacus, James W Bacus: Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope. Bacus Research Laboratories, Fitch Even Tabin & Flannery, May 1, 2001: US06226392 (92 worldwide citation)

A method is disclosed for using a computer controlled microscope system to provide a reconstructed, seamless image from several contiguous fields of view to show the architecture and spatial relationship of biological material in a specimen. The specimen is scanned with a microscope and a digital sc ...


10
James W Bacus: Analysis method and apparatus for biological specimens. Cell Analysis Systems, Fitch Even Tabin & Flannery, May 21, 1991: US05018209 (76 worldwide citation)

A method and apparatus are provided for selecting and analyzing a subpopulation of cells or cell objects for a certain parameter such as DNA, estrogen, and then measuring the selected cells. The observer in real time views a field of cells and then gates for selection based on the morphological crit ...