1
Hans T Thornander, John W Poore, Jason A Sholder, James R Thacker, David C Amundson: Physiologically responsive pacemaker and method of adjusting the pacing interval thereof. Siemens Elema, Bryant R Gold, Robert R Meads, December 15, 1987: US04712555 (327 worldwide citation)

A pacemaker and physiological sensor for use therewith that allows the rate at which the pacemaker delivers electrical stimulation pulses to the heart, or the escape interval during which a natural heart event must occur before an electrical stimulation pulse is delivered, to be adjusted as needed i ...


2
Kerry Bradley, James R Thacker: Apparatus and method for determining the relative position and orientation of neurostimulation leads. Advanced Bionics Corporation, Bryant R Gold, Victoria A Poissant, January 31, 2006: US06993384 (237 worldwide citation)

Interelectrode impedance or electric field potential measurements are used to determine the relative orientation of one lead to other leads in the spinal column or other body/tissue location. Interelectrode impedance is determined by measuring impedance vectors. The value of the impedance vector is ...


3
Todd K Whitehurst, Kelly H McClure, James R Thacker, James P McGivern: Treatment of hypertension. Advanced Bionics Corporation, Henricks Slavin & Holmes, Laura Haburay Bishop, December 26, 2006: US07155284 (214 worldwide citation)

Treatment of hypertension includes implantation of the discharge portion(s) of a catheter and/or electrical stimulation electrode(s) adjacent the tissue(s) to be stimulated. Stimulation pulses, i.e., drug infusion pulses and/or electrical pulses, are supplied by one or more implanted stimulators, th ...


4
John D H King, James R Thacker: Neural stimulation system providing auto adjustment of stimulus output as a function of sensed impedance. Boston Scientific Scimed, Vista IP Law Group, January 8, 2008: US07317948 (184 worldwide citation)

A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and ...


5
Carla Mann Woods, James R Thacker, David K L Peterson: Implantable system having rechargeable battery indicator. Advanced Bionics Corporation, Vista IP Law Group, February 13, 2007: US07177690 (177 worldwide citation)

A system and method for detecting the status of a rechargeable battery included within an implantable medical device. The medical device can incorporate a status indicator which signals the user concerning the battery status, e.g., low battery level. The signal may be audible or it may arise from an ...


6
Donald M Cohen, James R Thacker: Travenously placed defibrillation leads. Siemens Pacesetter, Bryant R Gold, Lisa P Weinberg, Leslie S Miller, March 12, 1991: US04998975 (112 worldwide citation)

A cardiac defibrillation system and method includes an epicardial electrode for making electrical contact with the epicardium from a position within the pericardial space, an endocardial electrode for making electrical contact with the endocardium of the heart, and means for making electrical contac ...


7
James R Thacker: Hemodynamically rate responsive pacemaker and method of automatically adjusting the escape and A-V intervals. Siemens Pacesetter, Lisa P Weinberg, Malcolm J Romano, June 18, 1991: US05024222 (100 worldwide citation)

In a rate responsive pacemaker, a physiological sensor is used to sense the physiological needs of the patient's heart and to control both the pacing rate and the A-V interval accordingly. A first adjustment means triggers the timing circuitry to adjust the stimulation rate to a slightly sub-optimal ...


8
Todd K Whitehurst, James P McGivern, Kelly H McClure, Goran N Marnfeldt, James R Thacker: Monitoring, preventing, and treating rejection of transplanted organs. Advanced Bionics Corporation, Laura Haburay Bishop, Peter K Johnson, November 29, 2005: US06970741 (83 worldwide citation)

An implantable system control unit (SCU) includes means for measuring tissue impedance or other condition to determine allograft health, in order to predict or detect allograft rejection. The SCU also includes at least two electrodes coupled to means for delivering electrical stimulation to a patien ...


9
James R Thacker, David K L Peterson, James P McGivern, Michael S Colvin: Neural stimulation lead fixation. Advanced Bionics Corporation, Bryant R Gold, Victoria A Poissant, August 29, 2006: US07099718 (59 worldwide citation)

An implantable lead having at least one electrode contact at or near its distal end prevents undesirable movement of the electrode contact from its initial implant location. One embodiment relates to a spinal cord stimulation (SCS) lead. A balloon may be positioned on the electrode lead array. The b ...


10
James E Barcel, Alvin H Weinberg, Shahram Moaddeb, James R Thacker: Pacemaker lead for sensing a physiologic parameter of the body. Siemens Pacesetter, Lisa P Weinberg, December 7, 1993: US05267564 (51 worldwide citation)

The present invention includes a body implantable lead having a multi-polar proximal connector, at least a first conductor coupled to at least one stimulating electrode, a sensor for sensing at least one physiologic parameter of the body, and a second and a third conductor coupled to the sensor. The ...



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