1
Dennis M Treu, Jeffrey H Burbank, James M Brugger: Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration. NxStage Medical, Ryan Kromholz & Manion S C, July 3, 2001: US06254567 (251 worldwide citation)

Peritoneal dialysis is performed by circulating peritoneal dialysis solution through a peritoneal cavity by conveying peritoneal dialysis solution through an inlet branch into the peritoneal cavity and by withdrawing peritoneal dialysis solution through an outlet branch from the peritoneal cavity. P ...


2
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge. NxStage Medical, Proskauer Rose, June 17, 2003: US06579253 (165 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


3
James M Brugger, Jeffrey H Burbank, Charles D Finch Jr, Hendrik K Kuiper: Method and apparatus for percutaneously accessing a pressure activated implanted port. VAScA, Townsend and Townsend and Crew, August 16, 2005: US06929631 (157 worldwide citation)

Methods and apparatus for percutaneously accessing an implanted port using an access tube which is periodically introduced to the implanted port. The apparatus is preferably an implantable port having a pressure-responsive valve element. It has been found that repeated passage of the access tube thr ...


4
Jeffrey H Burbank, C David Finch, James M Brugger, Hendrik E Kuiper: Valve port and method for vascular access. Vasca, Townsend and Townsend and Crew, December 28, 1999: US06007516 (156 worldwide citation)

An access port comprises a base and a flexible conduit. The port is subcutaneously implanted and the conduit is attached directly or indirectly to a blood vessel or other body lumen or cavity. An actuator mechanism is provided with a linkage which opens a valve in the port in response to percutaneou ...


5
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge. NxStage Medical, Proskauer Rose, February 8, 2005: US06852090 (144 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


6
James M Brugger, Jeffrey H Burbank, Dennis M Treu: Method and apparatus for leak detection in a fluid line. NxStage Medical, Proskauer Rose, June 3, 2003: US06572576 (142 worldwide citation)

One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Such systems draw blood at such a high rate that a loss of integrity in the blood circuit can be catastrophic. The most reliable leak detection method known ...


7
James M Brugger, Charles David Finch, Jeffrey H Burbank: Methods, systems, and kits for the extracorporeal processing of blood. NxStage Medical, Proskauer Rose, February 28, 2006: US07004924 (130 worldwide citation)

Methods, systems, and kits for extracorporeally circulating and processing blood are described. The systems include a pump, a processing unit, and blood drawn return lines for accessing a patient's vasculature. Blood flow through the return line is measured and pump speed controlled to maintain a de ...


8
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Measurement of fluid pressure in a blood treatment device. Nxstage Medical, Proskauer Rose, December 12, 2006: US07147613 (122 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


9
Martin Stillig, Jeffrey H Burbank, James M Brugger: Devices for potting a filter for blood processing. NxStage Medical, Proskauer Rose, March 9, 2004: US06702561 (117 worldwide citation)

A device for potting a filter is described. The device comprises a housing having a first hole in the first region communicating between the surface and the lumen, and a second hole in the second region communicating between the surface and the lumen. A ridge extends around the first hole and the se ...


10
Jeffrey H Burbank, C David Finch, James M Brugger: Hemofiltration system including ultrafiltrate purification and re-infusion system. NStage Medical, Proskauer Rose, June 24, 2003: US06582385 (117 worldwide citation)

A hemofiltration system is provided in which ultrafiltrate is purified by reverse osmosis for reinfusion. Non-sterile infusate concentrate is dialyzed into the purified ultrafiltrate and combined with cleared blood which is returned to the patient. In another system, a hemofilter is used to steriliz ...