1
Kyla Bjornson, Steven S Bondy, You chul Choi, Chien Hung Chou, Ruchika Mishra, James D Trenkle, Winston C Tse, Randall W Vivian, James G Taylor: Heterocyclic flaviviridae virus inhibitors. Gilead Sciences, Clark & Elbing, August 26, 2014: US08815858 (8 worldwide citation)

The invention is related to anti-viral compounds of formula (A) as defined in the claims, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well to processes and intermediates useful for preparing such compounds.


2

3
Manoj C Desai, Haolun Jin, Scott E Lazerwith, Hyung Jung Pyun, James G Taylor: Substituted 1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1,2-d]pyrazines and methods for treating viral infections. Gilead Sciences, May 30, 2017: US09663528 (1 worldwide citation)

Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with p ...


4
Amy Cagulada, Johann Chan, Lina Chan, Denise A Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G Taylor, Jonathan Tripp, Andrew W Waltman, Lawrence Yu: Synthesis of an antiviral compound. Gilead Sciences, September 13, 2016: US09440991 (1 worldwide citation)

The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.


5
Elizabeth M Bacon, Zhenhong R Cai, Xiaowu Chen, Jeromy J Cottell, Manoj C Desai, Mingzhe Ji, Haolun Jin, Scott E Lazerwith, Michael R Mish, Philip Anthony Morganelli, Hyung Jung Pyun, James G Taylor, Teresa Alejandra Trejo Martin: Substituted 2,3,4,5,7,9,13,13a-octahydro-1,5-methanopyrido[1′,2′:4,5]pyrazino[1,2-a][1,3]diazepines and methods for treating viral infections. GILEAD SCIENCES, July 31, 2018: US10035809

Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with p ...


6

7
Kyla L Bjornson, Kapil K Karki, John O Link, Hyung jung Pyun, Adam J Schrier, Kirk L Stevens, James G Taylor, Randall W Vivian, Jeff Zablocki, Sheila Zipfel: Inhibitors of hepatitis C virus. Gilead Sciences, Sheppard Mullin Richter & Hampton, April 11, 2017: US09617310

Compounds of formula I: or pharmaceutically acceptable salts thereof, wherein the various substituents are defined herein, methods of using said compounds, and pharmaceutical compositions containing said compounds.


8

9
Elizabeth M Bacon, Jeromy J Cottell, Ashley Anne Katana, Darryl Kato, Evan S Krygowski, John O Link, James G Taylor, Chinh Viet Tran, Teresa Alejandra Trejo Martin, Zheng Yu Yang, Sheila M Zipfel: Antiviral compounds. Gilead Pharmasset, Sheppard Mulllin Richter & Hampton, November 7, 2017: US09809600

The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


10
Amy Cagulada, Johann Chan, Lina Chan, Denise A Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondappally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G Taylor, Jonathan Tripp, Andrew W Waltman, Lawrence Yu: Synthesis of an antiviral compound. GILEAD SCIENCES, July 24, 2018: US10030033

The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.