1
Andrew J Berger, James F Brennan III, Ramanchandra R Dasari, Michael S Feld, Irving Itzkan, Kaz Tanaka, Yang Wang: Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes. Massachusetts Institute of Technology, Hamilton Brook Smith & Reynolds P C, April 1, 1997: US05615673 (128 worldwide citation)

The present invention relates to systems of methods of measuring selected analytes in blood and tissue using Raman spectroscopy to aid in diagnosis. More particularly, Raman spectra are collected and analyzed to measure the concentration of dissolved gases and other analytes of interest in blood. Me ...


2
James F Brennan III, Patrick C Chou, Harry L T Lee, Rajeev J Ram, Hermann A Haus, Erich P Ippen: Method and apparatus for generating frequency modulated pulses. 3M Innovative Properties Company, Gregg J Rosenblatt, December 21, 2004: US06834134 (50 worldwide citation)

A method and apparatus are provided for generating short (e.g., picosecond) pulses using a 2 section 1553 nm DBR laser without gain switching nor external modulation. The center wavelength of the DBR section is modulated at 0.5 GHz to generate a constant amplitude frequency modulated optical wave La ...


3
James F Brennan III, Dwayne L LaBrake: Long-length continuous phase Bragg reflectors in optical media. 3M Intellectual Properties Company, Nestor F Ho, June 11, 2002: US06404956 (38 worldwide citation)

A long length continuous phase Bragg reflector and the method and an apparatus for writing the gratings into an optical fiber. The method includes the steps of providing a photosensitive optical fiber and a writing beam. A periodic intensity distribution of period &Lgr; is created from the writing b ...


4
James F Brennan III, Dwayne L LaBrake, Patrick C Chou, Hermann A Haus: Method and apparatus for arbitrary spectral shaping of an optical pulse. 3M Innovative Properties Company, Massachusetts Institute of Technology, Nestor F Ho, February 27, 2001: US06195484 (37 worldwide citation)

A method and an apparatus for stretching an optical pulse and shaping its spectrum. The method includes the step of: providing a an optical fiber element having a first long length fiber Bragg grating having a refractive index perturbation of varying periodicity. The optical pulse is launched into t ...


5
James F Brennan III, Dwayne LaBrake, Gerard A Beauchesne, Ronald P Pepin: Method for fabrication of in-line optical waveguide index grating of any length. Minnesota Mining and Manufacturing Company, Nestor F Ho, June 15, 1999: US05912999 (29 worldwide citation)

A method and an apparatus for writing apodized Bragg gratings into an optical fiber. The method includes the steps of providing a photosensitive optical fiber and a writing beam. A periodic intensity distribution of period .LAMBDA. is created from the writing beam and the optical fiber is translated ...


6
James F Brennan III, Diann A Sloan, Maureen T Fahey, James C Novack: Accelerated method for increasing the photosensitivity of a glassy material. 3M Innovative Properties Company, Néstor F Ho, November 6, 2001: US06311524 (28 worldwide citation)

A method for rapidly increasing the photosensitivity of an optical fiber comprising the step of providing an optical fiber comprising a glassy material and a thermally-stable coating. The thermally-stable coating has a thermally-stable exposure band, wherein desired time/temperature exposure paramet ...


7
James F Brennan III: Optical catheter configurations combining raman spectroscopy with optical fiber-based low coherence reflectometry. Prescient Medical, Patton Boggs, May 31, 2011: US07952719 (25 worldwide citation)

The present invention provides apparatuses and methods for sample analysis, such as tissue analysis, that integrate high wavenumber (HW) Raman spectroscopy for chemical composition analysis and optical coherence tomography (OCT) to provide depth and morphological information. The invention also prov ...


8
James F Brennan III, Dwayne L LaBrake: Method for writing arbitrary index perturbations in a wave-guiding structure. 3M Innovative Company, Nestor F Ho, March 7, 2000: US06035083 (20 worldwide citation)

A method and an apparatus for writing arbitrary refractive index perturbations along an optical waveguide. The method includes the steps of providing a waveguide having a photosensitive region and providing a writing beam of actinic radiation having a nominal diameter D, the writing beam defining an ...


9
James F Brennan III, Laurent Vaissié, Michael Mielke, Tolga Yilmaz: Pulse selecting in a chirped pulse amplification system. Raydiance, Carr & Ferrell, August 31, 2010: US07787175 (16 worldwide citation)

A chirped pulse amplification (CPA) system and method is described wherein a pulse selector is added after a final amplifier in the system. The pulse selector is configured to select amplified pulses such that the system output repetition rate of the CPA system is below an ASE-limiting repetition ra ...


10
James F Brennan III, Laurent Vaissie, Michael Mielke: Bragg fibers in systems for the generation of high peak power light. Raydiance, Carr & Ferrell, March 25, 2008: US07349452 (15 worldwide citation)

The present invention generally concerns the use of Bragg optical fibers in chirped pulse amplification systems for the production of high-pulse-energy ultrashort optical pulses. A gas-core Bragg optical fiber waveguide can be advantageously used in such systems to stretch the duration of pulses so ...