1
James E Kipp, Joseph Chung Tak Wong, Mark J Doty, Christine L Rebbeck: Microprecipitation method for preparing submicron suspensions. Baxter International, Mark J Buonaiuto, Joseph A Fuchs, August 19, 2003: US06607784 (39 worldwide citation)

The present invention provides a method for preparing submicron sized particles of an organic compound, the solubility of which is greater in a water-miscible first solvent than in a second solvent which is aqueous, the process including the steps of (i) dissolving the organic compound in the water- ...


2
James E Kipp, Joseph Chung Tak Wong, Mark J Doty, Christine L Rebbeck: Microprecipitation method for preparing submicron suspensions. Baxter International, Michael C Mayo, Joseph A Fuchs, March 22, 2005: US06869617 (25 worldwide citation)

The present invention provides a method for preparing submicron sized particles of an organic compound, the solubility of which is greater in a water-miscible first solvent than in a second solvent which is aqueous, the process including the steps of: (i) dissolving the organic compound in the water ...


3
James E Kipp, Joseph Chung Tak Wong, Mark J Doty, Jane Werling, Christine L Rebbeck, Sean Brynjelsen: Method for preparing submicron particle suspensions. Baxter International, Michael C Mayo, Joseph A Fuchs, April 26, 2005: US06884436 (25 worldwide citation)

The present invention provides a method for preparing a suspension of a pharmaceutically-active compound, the solubility of which is greater in a water-miscible first organic solvent than in a second solvent which is aqueous. The process includes the steps of: (i) dissolving a first quantity of the ...


4
Sean Brynjelsen, Mark Doty, James E Kipp, Nailesh Jayswal, Krishnaswamy Narayanan: Preparation of submicron sized nanoparticles via dispersion lyophilization. Baxter International, Michael C Mayo, Joseph A Fuchs, Thomas C Basso, December 28, 2004: US06835396 (17 worldwide citation)

The present invention relates to a process for preparing submicron sized nanoparticles of a poorly water soluble compound by lyophilizing a dispersion or microdispersion of a multiphase system having an organic phase and an aqueous phase, the organic phase having the poorly water soluble organic com ...


5
James E Kipp, Joseph Chung Tak Wong, Mark J Doty, Christine L Rebbeck: Microprecipitation method for preparing submicron suspensions. Baxter International, Michael C Mayo, May 2, 2006: US07037528 (12 worldwide citation)

The present invention provides a method for preparing submicron sized particles of an organic compound, the solubility of which is greater in a water-miscible first solvent than in a second solvent which is aqueous, the process including the steps of: (i) dissolving the organic compound in the water ...


6
Jane Werling, James E Kipp, Rajaram Sriram, Mark J Doty: Method for preparing submicron suspensions with polymorph control. Baxter International, Michael C Mayo, Raymond M Mehler, December 20, 2005: US06977085 (11 worldwide citation)

The present invention provides a method for preparing a suspension of a pharmaceutically-active compound, the solubility of which is greater in a water-miscible first organic solvent than in a second solvent which is aqueous. The process includes the steps of: (i) dissolving a first quantity of the ...


7
James E Kipp, Mark J Doty, Christine L Rebbeck, Sean Brynjelsen, Jamie Teresa Konkel: Compositions of and method for preparing stable particles in a frozen aqueous matrix. Baxter International, Michael C Mayo, Raymond M Mehler, September 26, 2006: US07112340 (5 worldwide citation)

The present invention discloses a composition of a stable suspension of a poorly water soluble pharmaceutical agent or cosmetic in the form of particles of the pharmaceutical agent or cosmetic suspended in a frozen aqueous matrix and method for its preparation. The composition is stable for a prolon ...


8

9
James E Kipp, Joseph Chung Tak Wong, Mark J Doty, Christine L Rebbeck, Sean Brynjelsen: Microprecipitation method for preparing submicron suspensions. Baxter International, Michael C Mayo, Joseph A Fuchs, October 4, 2005: US06951656 (2 worldwide citation)

The present invention provides a method for preparing submicron sized particles of an organic compound, the solubility of which is greater in a water-miscible first solvent than in a second solvent which is aqueous, the process including the steps of: (i) dissolving the organic compound in the water ...


10
James E Kipp, Joseph Chung Tak Wong, Monte Wisler, Rhonda Garcia: Methods and apparatuses for the comminution and stabilization of small particles. Baxter International, Marshall Gerstein & Borun, March 31, 2009: US07511079 (2 worldwide citation)

Methods and apparatuses for comminuting and stabilizing small particles are provided. In one embodiment, an apparatus moves an organic compound dissolved in a solvent to form a suspension of particles in a first fluid stream and moves the suspension in a second fluid stream, wherein the second fluid ...