1
Ivan Lieberburg, James Callaway, Michael Grundman: Treatment of amyloidogenic diseases. Janssen Alzheimer Immunotherapy, Wyeth, Alston & Bird, December 24, 2013: US08613920 (2 worldwide citation)

The invention provides preferred dosage ranges, maximum concentrations, average concentrations and monitoring regimes for use in treatment of Alzheimer's disease using antibodies to Aβ. The invention also provides monitoring regimes that can assess changes in symptoms or signs of the patient followi ...


2
Ronald Black, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M Gregg, Jack Steven Jacobsen, Davinder Gill, Lioudmila Tchistiakova, Angela Widom: Immunotherapy regimes dependent on ApoE status. Wyeth, JANSSEN SCIENCES IRELAND UC, Alston & Bird, May 9, 2017: US09644025

The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient.


3
Ivan Lieberburg: Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds. Elan Pharmaceuticals, Finnegan Henderson Farabow Garrett & Dunner, April 2, 2013: US08410115

Alpha 4 inhibitors are used in treatment of inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn's Disease, rheumatoid arthritis and asthma. Rare occurrences of progressive multifocal leucoencephalopathy during treatment with an alpha-4 agent suggest the possibility that it may be ...


4
Ivan Lieberburg: Methods of treating inflammatory and autoimmune diseases with natalizumab. Biogen, Nathan Edwards, Ginger R Dreger, Arnold & Porter, November 15, 2016: US09493567

Natalizumab is a safe and efficacious treatment for inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn's Disease, and rheumatoid arthritis. Rare occurrences of progressive multifocal leucoencephalopathy during treatment suggest the possibility that it may be related to natalizum ...


5
Theodore A Yednock, Stephen B Freedman, Ivan Lieberburg, Michael A Pleiss, Andrei W Konradi, George Shopp, Elizabeth Messersmith: Methods and compositions for treating rheumatoid arthritis. Elan Pharmaceuticals, Crowell & Moring, October 20, 2009: US07605166

This application relates to methods and compositions for treating rheumatoid arthritis by administering a combination therapy comprising methotrexate and an antibody to alpha-4 integrin or an immunologically active antigen binding fragment in therapeutically effective amounts. The application also r ...


6
Elizabeth Messersmith, Ivan Lieberburg: Methods and compositions for treating liquid tumors. Elan Pharmaceuticals, Crowell & Moring, September 18, 2012: US08269009

The application relates to a method of using compositions having anti-alpha-4 integrin and/or anti-alpha-9 integrin activity to inhibit liquid tumor growth, malignancies thereof and/or development of metastases thereof that involve expression of an alpha-4 integrin and/or alpha-9 integrin. Pharmaceu ...


7
Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M Gregg, Wagner Zago, Manuel J Buttini, Gene G Kinney: Use of tau to monitor immunotherapy. JANSSEN SCIENCES IRELAND UC, Wyeth, Alston & Bird, March 1, 2016: US09272030

The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.


8
Hayato Miyachi, Ivan Lieberburg: Methods of using zonisamide as an adjunctive therapy for partial seizures. Wilmer Cutler Pickering Hale And Dorr, March 17, 2005: US20050059718-A1

Methods of using zonisamide as an adjunctive therapy for partial seizures are disclosed. In particular, the methods enhance the safety of patients taking pharmaceutical formulations of zonisamide by providing information that increases the awareness of monoclonal gammopathy of undetermined significa ...


9
Theodore A Yednock, Stephen B Freedman, Ivan Lieberburg, Michael A Pleiss, Andrei W Konradi, George Shopp, Elizabeth Messersmith: Methods and compositions for treating rheumatoid arthritis. Elan Pharmaceuticals, Burns Doane Swecker & Mathis L, March 24, 2005: US20050065192-A1

This application relates to methods and compositions for treating rheumatoid arthritis by administering a combination therapy comprising methotrexate and an antibody to alpha-4 integrin or an immunologically active antigen binding fragment in therapeutically effective amounts. The application also r ...


10
Ivan Lieberburg: Methods of improving the safety of zonisamide therapy. Finnegan Henderson Farabow, Garrett & Dunner, February 24, 2005: US20050043773-A1

Methods to increase the safety of patients taking pharmaceutical formulations of zonisamide by providing information that increases the awareness of pancreatitis as a possible side effect wherein both the patient and treating physicians and other medical care providers may monitor effectively for pa ...