1
Rabih O Darouiche, Issam Raad: Antimicrobial impregnated catheters and other medical implants. Baylor College of Medicine Board of Regents, The University of Texas System, Thomas D Paul, Fulbright & Jaworski L, May 11, 1999: US05902283 (148 worldwide citation)

A non-metallic antimicrobial impregnated medical implant, such as a catheter, and a method for impregnating a non-metallic medical implant with an antimicrobial agent is provided. The method for making the impregnated implant comprises the steps of forming an antimicrobial composition of an effectiv ...


2
Rabih O Darouiche, Issam Raad: Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent. Baylor College of Medicine, University of Texas System, Fulbright & Jaworski L, April 29, 1997: US05624704 (99 worldwide citation)

A non-metallic antimicrobial impregnated medical implant, such as a catheter, and a method for impregnating a non-metallic medical implant with an antimicrobial agent is provided. The method for making the impregnated implant comprises the steps of forming an antimicrobial composition of an effectiv ...


3
Issam Raad, Robert J Sherertz: M-EDTA pharmaceutical preparations and uses thereof. Univ of TX MD Anderson Cancer Center, Arnold White & Durkee, November 8, 1994: US05362754 (72 worldwide citation)

Disclosed are pharmaceutical compositions of a mixture of minocycline and EDTA (M-EDTA) and methods of using the compositions in maintaining the patency of a catheter port. Methods for inhibiting the formation of polysaccharide-rich glycocalyx (such as the glycocalyx of staphylococcal organisms) are ...


4
Robert Tcholakian, Issam Raad: Multipurpose anti-microbial silastic sheath system for the prevention of device-related infections. Board of Regents University of Texas Systems, Arnold White and Durkee, October 13, 1998: US05820607 (65 worldwide citation)

The present invention relates generally to indwelling medical devices. In particular, there is provided a device constructed from permeable or nonpermeable material having a pharmacologically active ingredient layer surrounding the device, and an outer sheath which is permeable to the pharmacologica ...


5
Issam Raad, Robert Sherertz, Ray Hachem: EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections. Board of Regents The University of Texas System, Fulbright & Jaworski, January 21, 2003: US06509319 (41 worldwide citation)

A pharmaceutical composition comprising at least one antifungal agent and at least one chelator, and a method for administering the pharmaceutical composition to a patient having a fungal infection. Another aspect provides a pharmaceutical composition comprising at least one chelator, at least one a ...


6
Issam Raad, Robert Sherertz: Chelators in combination with biocides: treatment of microbially induced biofilm and corrosion. Wake Forest University, Board of Regents The University of Texas System, Fulbright & Jaworski, July 31, 2001: US06267979 (36 worldwide citation)

Control of biofouling in pipes or aqueous systems via the use of compositions and methods that include the combination of a chelator with an antimicrobial agent.


7
Issam Raad, Robert Sheretz, Ray Hachem: EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections. Wake Forest University, Board of Regents The University of Texas Sysytem, Fulbright & Jaworski, December 26, 2000: US06165484 (28 worldwide citation)

A pharmaceutical composition comprising at least one antifungal agent and at least one chelator, and a method for administering the pharmaceutical composition to a patient having a fungal infection. Another aspect provides a pharmaceutical composition comprising at least one chelator, at least one a ...


8
Issam Raad, Hend A Hanna, Nabeel Nabulsi: Medical devices with broad spectrum antimicrobial activity. Board of Regents the University of Texas System, Fulbright & Jaworski, January 26, 2010: US07651661 (14 worldwide citation)

The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pat ...


9
Issam Raad: Antimicrobial flush solutions. Board of Regents the University of Texas System, Fulbright & Jaworski, October 13, 2009: US07601731 (10 worldwide citation)

The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devic ...


10
Issam Raad: Antimicrobial flush solutions. Board of Regents The University of Texas System, Parker Highlander PLLC, July 14, 2015: US09078441 (6 worldwide citation)

The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devic ...