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Natsugari Hideaki, Ikeda Hitoshi, Ishimaru Takenori, Doi Takayuki: Condensed heterocyclic compounds, their production and use.. Takeda Chemical Industries, March 9, 1994: EP0585913-A2 (58 worldwide citation)

Novel compound represented by the formula: wherein ring A may be substituted; ring B represents an optionally substituted benzene ring; either X or Y represents -NR- (R represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted hydroxyl group or an optionally ...


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Natsugari Hideaki, Ishimaru Takenori, Doi Takayuki, Ikeura Yoshinori, Kimura Chiharu: Cyclic compounds, their production and use as tachykinin receptor antagonists. Takeda Chemical Industries, September 25, 1996: EP0733632-A1 (38 worldwide citation)

Novel compounds of the following general formula or salts thereof. wherein Ring M is a heterocyclic ring having -N=C and R are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B repres ...


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Natsugari Hideaki, Ishimaru Takenori, Doi Takayuki: Heterocyclic compounds, their production and use.. Takeda Chemical Industries, May 10, 1995: EP0652218-A1 (15 worldwide citation)

A novel compound represented by the formula: wherein Ring A and Ring B respectively stands for an optionally substituted homo- or hetero-cyclic ring, and at least one of them stands for an optionally substituted heterocyclic ring stand; Ring C stands for an optionally substituted benzene ring; R sta ...


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Kanamaru Tsuneo, Ishimaru Takenori, Muroi Masayuki: Naphthopyran derivatives and use thereof.. Takeda Chemical Industries, October 18, 1989: EP0337413-A2 (1 worldwide citation)

The present invention relates to an aromatase inhibiting composition which contains a compound of the formula: wherein R is hydroxy, lower alkoxy or amino which may be substituted by lower alkyl; R is hydrogen or lower alkyl; and A is hydrogen, a group of the formula in which R is hydroxy, lower alk ...


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Natsugari Hideaki, Ikeda Hitoshi, Ishimaru Takenori, Doi Takayuki: Composes heterocycliques condenses, procede de production et emploi, Condensed heterocyclic compounds, their production and use. Takeda Chemical Industries, Takeda Pharmaceutical Company, FETHERSTONHAUGH & CO, August 9, 2005: CA2105518

Novel compound represented by the formula: Image wherein ring A may be substituted; ring B represents an optionally substituted benzene ring; either X or Y represents -NR1- (R1 represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted hydroxyl group or an opt ...


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Okazaki Hisayoshi, Ishimaru Takenori, Ohta Kazuhiko: Substance p-23924 ayant une activite physiologique, production et utilisation, Physiologically active substance p-23924, its production and use. Takeda Chemical Industries, FETHERSTONHAUGH & CO, June 17, 1986: CA1206111

ABSTRACT OF THE DISCLOSURE The compound of the formula: Imagewherein R1 is hydrogen, methyl or hydroxymethyl, R2 is hydrogen ormethoxy, R3 is hydroxy or methoxy, and R4 is hydrogen or a group Image is novel, and the compound is of use as inhibitorsof animal tissue fibrosis, or biochemical reagents. ...


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Shirafuji Hideo, Tsubotani Shigetoshi, Ishimaru Takenori, Harada Setsuo: Compound tan-1251, its derivatives, their production and use. Takeda Chemical Industries, Shirafuji Hideo, Tsubotani Shigetoshi, Ishimaru Takenori, Harada Setsuo, IWATA Hiroshi, September 19, 1991: WO/1991/013887

A compound of formula (I), wherein R?1¿ is hydrogen or a hydrocarbon residue which may be substituted; R?2¿ is oxo or hydrogen plus hydroxy which may be acylated; R?3¿ is a hydrogen or hydroxy which may be acylated; at least one of the dotted lines represents a single bond, or a salt thereof, has po ...


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Shirafuji Hideo, Tsubotani Shigetoshi, Ishimaru Takenori, Harada Setsuo: Compound tan-1251, its derivatives, their production and use.. Takeda Chemical Industries, March 24, 1993: EP0532752-A1

PCT No. PCT/JP91/00295 Sec. 371 Date Apr. 22, 1991 Sec. 102(e) Date Apr. 22, 1991 PCT Filed Mar. 5, 1991 PCT Pub. No. WO91/13887 PCT Pub. Date Sep. 19, 1991.A compound of the formula wherein R1 is hydrogen or a hydrocarbon residue which may be substituted; R2 is oxo or hydrogen plus hydroxy which ma ...