1
Imad Libbus, Bruce H KenKnight, Julia Moffitt, Yatheendhar D Manicka: Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, August 21, 2007: US07260431 (354 worldwide citation)

A method and device for delivering ventricular resynchronization pacing therapy in conjunction with electrical stimulation of nerves which alter the activity of the autonomic nervous system is disclosed. Such therapies may be delivered by an implantable device and are useful in preventing the delete ...


2
Badri Amurthur, Steven D Girouard, Imad Libbus: Distributed neuromodulation system for treatment of cardiovascular disease. Cardiac Pacemakers, Schwegman Lundberg Woessner P A, February 16, 2010: US07664548 (129 worldwide citation)

A distributed system is described that employs electrical neural stimulation to modulate autonomic activity and which allows titration of the neural stimulation therapy in accordance with physiological measurements reflective of autonomic activity and/or physiological variables affected by the neura ...


3
Julia Moffitt, Imad Libbus: Transvascular neural stimulation device. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, March 3, 2009: US07499748 (126 worldwide citation)

This document discusses, among other things, apparatus, systems, and methods for transvascularly stimulation of a nerve or nerve trunk. In an example, an apparatus is configured to transvascularly stimulate a nerve trunk through a blood vessel. The apparatus includes an expandable electrode that is ...


4
Mark J Bly, Badri Amurthur, Kristofer J James, Imad Libbus, Yatheendhar D Manicka, Scott T Mazar, Jerry S Wang: Adherent device with multiple physiological sensors. Corventis, Kilpatrick Townsend & Stockton, October 9, 2012: US08285356 (121 worldwide citation)

An adherent device to monitor a patient for an extended period comprises a breathable tape. The breathable tape comprises a porous material with an adhesive coating to adhere the breathable tape to a skin of the patient. At least one electrode is affixed to the breathable tape and capable of electri ...


5
Imad Libbus: Baroreflex therapy for disordered breathing. Cardiac Pacemakers, Hollingsworth & Funk, March 20, 2007: US07194313 (113 worldwide citation)

A baroreflex stimulator is described that treats disordered breathing in a patient. The stimulator includes a pulse generator to provide a baroreflex stimulation signal through an electrode, and a modulator to modulate the baroreflex stimulation signal based on a circadian rhythm template.


6
Imad Libbus, Paul A Haefner, Aaron McCabe, Yi Zhang: Method and apparatus for synchronizing neural stimulation to cardiac cycles. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, June 2, 2009: US07542800 (108 worldwide citation)

A neural stimulator senses a reference signal indicative of cardiac cycles each including a predetermined type timing reference event using a sensor external to the heart and blood vessels. The delivery of the neural stimulation pulses are synchronized to that timing reference event. Examples of the ...


7
Imad Libbus, Yatheendhar D Manicka, Mark J Bly: Adherent device for sleep disordered breathing. Corventis, Kilpatrick Townsend & Stockton, August 21, 2012: US08249686 (105 worldwide citation)

An adherent device is configured to adhere to the skin of the patient with an adherent patch, for example breathable tape, coupled to at least four electrodes. The device comprises impedance circuitry coupled to the at least four electrodes and configured to measure respiration of the patient to det ...


8
Imad Libbus, Andrew P Kramer: Automatic neural stimulation modulation based on activity and circadian rhythm. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, August 24, 2010: US07783353 (104 worldwide citation)

According to an embodiment of a method for providing neural stimulation, activity is sensed, and neural stimulation is automatically controlled based on the sensed activity. An embodiment determines periods of rest and periods of exercise using the sensed activity, and applies neural stimulation dur ...


9
Imad Libbus, Julio C Spinelli: Baroreflex modulation to gradually decrease blood pressure. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, February 3, 2009: US07486991 (104 worldwide citation)

An aspect of the present subject matter relates to a baroreflex stimulator. An embodiment of the stimulator includes a pulse generator to provide a baroreflex stimulation signal through an electrode, and a modulator. The modulator modulates the baroreflex stimulation signal to increase the barorefle ...


10
Julia Moffitt, Sophia Wang, Bruce H KenKnight, Imad Libbus: Combined neural stimulation and cardiac resynchronization therapy. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, September 8, 2009: US07587238 (100 worldwide citation)

Methods and devices for delivering cardiac therapy to a patient are provided. Various implantable device embodiments comprise a plurality of leads and a controller. The leads include at least one lead to be positioned within a lead path to deliver ventricular pacing pulses and to deliver neural stim ...