1
Jean Michel Vernier, Nicholas D P Cosford, Ian A McDonald: Substituted pyridine compounds useful as modulators of acetylcholine receptors. Merck & Co, David Rubin, David L Rose, October 14, 2003: US06632823 (40 worldwide citation)

In accordance with the present invention, a novel class of substituted pyridine compounds (optionally containing ether, ester, amide, ketone or thioether substitutions) that promote the release of ligands involved in neurotransmission have been discovered. In a particular aspect compounds of the pre ...


2
Michael G Palfreyman, Philippe Bey, Ian A McDonald: Inhibitors of lysyl oxidase. Merrell Dow Pharmaceuticals, Michael J Sayles, October 12, 1993: US05252608 (26 worldwide citation)

This invention relates to certain inhibitors of lysyl oxidase and their use in the treatment of diseases and conditions associated with the abnormal deposition of collagen.


3
Michael G Palfreyman, Philippe Bey, Ian A McDonald: Inhibitors of lysyl oxidase. Merrell Dow Pharmaceuticals, Michael J Sayles, January 26, 1993: US05182297 (25 worldwide citation)

This invention relates to certain inhibitors of lysyl oxidase and their use in the treatment of diseases and conditions associated with the abnormal deposition of collagen.


4
Ian A McDonald, Jeffrey P Whitten, Nicholas D Cosford: Modulators of acetylcholine receptors. Sibia Neurosciences, Stephen E Gray Cary Ware & Freidenrich Reiter, March 3, 1998: US05723477 (22 worldwide citation)

The present invention provides a class of pyridine compounds which are modulators of acetylcholine receptors, i.e., compounds which displace acetylcholine receptor ligands from their binding sites. Invention compounds may act as agonists, partial agonists, antagonists or allosteric modulators of ace ...


5
Ian A McDonald, Jeffrey P Whitten, Nicholas D Cosford: Modulators of acetylcholine receptors. SIBIA Neurosciences, Stephen E Gray Cary Ware & Freidenrich Reiter, December 30, 1997: US05703100 (20 worldwide citation)

In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds may act as agonists, partial agonists, antag ...


6
Ian A McDonald, Jeffrey P Whitten, Nicholas D Cosford: Modulators of acetylcholine receptors. SIBIA Neurosciences, Stephen E Reiter, Pretty Schroeder Brueggemann & Clark, January 14, 1997: US05594011 (20 worldwide citation)

In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds may act as agonists, partial agonists, antag ...


7
Michael G Palfreyman, Philippe Bey, Ian A McDonald: Inhibitors of lysyl oxidase. Merrell Dow Pharmaceuticals, Michael J Sayles, October 22, 1991: US05059714 (19 worldwide citation)

This invention relates to certain inhibitors of lysyl oxidase and their use in the treatment of diseases and conditions associated with the abnormal deposition of collagen.


8
Michael G Palfreyman, Philippe Bey, Ian A McDonald: Inhibitors of lysyl oxidase. Merrell Dow Pharmaceuticals, Michael J Sayles, October 23, 1990: US04965288 (19 worldwide citation)

This invention relates to certain inhibitors of lysyl oxidase and their use in the treatment of diseases and conditions associated with the abnormal deposition of collagen.


9
Michael G Palfreyman, Ian A McDonald, Philippe Bey: Inhibitors of lysyl oxidase. Merrell Dow Pharmaceuticals, Michael J Sayles, July 24, 1990: US04943593 (19 worldwide citation)

This invention relates to certain inhibitors of lysyl oxidase and their use in the treatment of diseases and conditions associated with the abnormal deposition of collagen.


10
Michael G Palfreyman, Philippe Bey, Ian A McDonald: Inhibitors of lysyl oxidase. Merrell Dow Pharmaceuticals, Michael J Sayles, June 4, 1991: US05021456 (19 worldwide citation)

This invention relates to certain inhibitors of lysyl oxidase and their use in the treatment of diseases and conditions associated with the abnormal deposition of collagen.