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Allen Shelley, Andrews Steven S, Condroski Kevin Ronald, Haas Julia, Huang Lily, Jiang Yutong, Kercher Timothy, Seo Jeongbeob: Substituted pyrazolo[1,5- a]pyrimidine compounds as TRK kinase inhibitors. Array Biopharma, chen an, July 18, 2012: CN201080040095

Compounds of Formula (I) and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerativ ...


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Boys Mark Laurence, Burgess Laurence E, Groneberg Robert D, Harvey Darren M, Huang Lily, Kercher Timothy, Kraser Christopher F, Laird Ellen, Tarlton Eugene, Zhao Qian: 5, 7-substituted-imidazo [1, 2-c] pyrimidines as inhibitors of jak kinases. Array Biopharma, chen an, March 20, 2013: CN201180029128

Compounds of Formula I and stereoisomers and pharmaceutically acceptable salts and solvates are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders a ...