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Hu Zhihao, Valle Fernando: Enhanced production of fatty acid derivatives. Ls9, Hu Zhihao, Valle Fernando, SONG Victor L, October 2, 2008: WO/2008/119082 (75 worldwide citation)

Genetically engineered cells and microorganisms are provided that produce products from the fatty acid biosynthetic pathway (fatty acid derivatives), as well as methods of their use. The products are particularly useful as biofuels.


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Hu Zhihao: Methods and compositions for producing fatty alcohols. LS9, Superko Colleen, June 3, 2010: WO/2010/062480 (15 worldwide citation)

Methods and compositions, including nucleotide sequences, amino acid sequences, and host cells, for producing fatty alcohols are described.


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HU ZHIHAO: Systems and methods for the production of mixed fatty esters. LS9, Altman Daniel E, February 25, 2010: WO/2010/022090 (12 worldwide citation)

Disclosed herein are various embodiments regarding the production of mixed fatty esters. Disclosed herein are various embodiments regarding the use of mixed alcohol compositions for the production of fatty esters.


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GREENFIELD Derek L, HOM Louis G, SANCHEZ RIERA Fernando A, HU Zhihao, ARLAGADDA Vikranth, GROBAN Eli S, FRYKMAN Scott A: PROCÉDÉS ET COMPOSITIONS POUR UNE PRODUCTION AMÉLIORÉE DES ACIDES GRAS ET LEURS DÉRIVÉS, METHODS AND COMPOSITIONS FOR IMPROVED PRODUCTION OF FATTY ACIDS AND DERIVATIVES THEREOF. LS9, GREENFIELD Derek L, HOM Louis G, SANCHEZ RIERA Fernando A, HU Zhihao, ARLAGADDA Vikranth, GROBAN Eli S, FRYKMAN Scott A, JUDGE Linda R, November 15, 2012: WO/2012/154329 (3 worldwide citation)

The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, and engineered host cells for producing fatty acids and derivates of fatty acids such as acyl-CoA, terminal olefins, fatty aldehydes, fatty alcohols, alkanes, alkenes, wax esters, ketones and ...


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Hutchinson C Richard, Reid Ralph C, Hu Zhihao, Rascher Andreas, Schirmer Andreas, Mcdaniel Robert: Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthases and accessory proteins, and uses thereof. Kosan Biosciences, Hutchinson C Richard, Reid Ralph C, Hu Zhihao, Rascher Andreas, Schirmer Andreas, Mcdaniel Robert, APPLE Randolph T, December 24, 2003: WO/2003/106653 (1 worldwide citation)

Abstract The invention relates to recombinant polyketide synthase enzymes, polyketide modifying proteins, and other proteins involved in polyketide biosynthesis or function. The invention provides domains of geldanamycin and herbimycin polyketide synthases, polynucleotides that encode such enzymes, ...


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HU Zhihao, LEE Grace J, SCHIRMER Andreas, ZAKHARYEVICH Kseniya, GREENFIELD Derek L, BARON Tarah S, HOLDEN Kevin: PRODUCTION DACIDES GRAS À CHAÎNE RAMIFIÉE ET DE LEURS DÉRIVÉS DANS DES CELLULES MICROBIENNES RECOMBINANTES, PRODUCTION OF BRANCHED CHAIN FATTY ACIDS AND DERIVATIVES THEREOF IN RECOMBINANT MICROBIAL CELLS. LS9, HU Zhihao, LEE Grace J, SCHIRMER Andreas, ZAKHARYEVICH Kseniya, GREENFIELD Derek L, BARON Tarah S, HOLDEN Kevin, KILYK JR John, July 19, 2012: WO/2012/096686 (1 worldwide citation)

Recombinant microbial cells are provided which have been engineered to produce branched chain products such as branched fatty acid derivatives by the fatty acid biosynthetic pathway, and methods of making branched fatty acid derivatives using the recombinant microbial cells.


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HU ZHIHAO, VALLE FERNANDO: [fr] Production améliorée de dérivés dacide gras, [de] Verbesserte Herstellung von Fettsäurederivaten, [en] Enhanced production of fatty acid derivatives. LS9, May 22, 2013: EP2594633-A1

[en] Genetically engineered cells and microorganisms are provided that produce products from the fatty acid biosynthetic pathway (fatty and derivatives), as well as methods of their use. The products are particularly useful as biofuels.



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