1
Andrieux Jean, Houssin Raymond, Yous Said Laboratoire de Chimi, Guardiola Beatrice, Lesieur Daniel: Naphthalene derivatives, procedure for their preparation and pharmaceutical compositions containing them.. Adir, September 18, 1991: EP0447285-A1 (96 worldwide citation)

Composés de formule générale : dans laquelle R, R1 et R2 sont définis dans la description. Les composés de formule (1) sont utiles dans le traitement de désordres de système nerveux central.


2
Ait Mansour Hamid, Taverne Thierry, Houssin Raymond, Lesieur Isabelle, Depreux Patrick, Adam Gerard, Caignard Daniel Henri, Renard Pierre, Rettori Marie Claire: Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them.. Adir, September 27, 1995: EP0673934-A1 (2 worldwide citation)

Aminoalkyl benzothiazolinones of formula (I), their optical isomers, and their acid and base addn. salts, are new. R1 = H or opt. substd. alkyl; R2 = -(CH2)3-N(R3)R4 (gp.R21), or a gp. of formula (R22); R3, R4 = H, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl or -(CH2)m-aryl (opt. substd. on ...


3
Andrieux Jean, Houssin Raymond, Yous Said, Guardiola Beatrice, Lesieur Daniel: Derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent, Derivatives having a naphthalenic structure; process for preparing the same and pharmaceutical compositions containing them. Les Laboratoires Servier, OGILVY RENAULT SENCRLSRL, August 18, 1998: CA2036876

Compos�s de formule g�n�rale: Imagedans laquelle A repr�sente un groupement Image R repr�sente un groupement alkyle inf�rieurlin�aire ou ramifi�,R1 repr�sente un atome d'hydrog�ne ou ungroupement alkyle inf�rieur lin�aire ouramifi�,R2 repr�sente un atome d'hydrog�ne, ungroupement alkyle inf�rieur li ...


4
Andrieux Jean, Houssin Raymond, Yous Said, Guardiola Beatrice, Lesieur Daniel: Novel derivative having naphthalene structure, preparation thereof, and pharmaceutical composition containing same. Adir, February 21, 1995: JP1995-048331

PURPOSE: To provide a novel 1-alkoxy-(2-acylaminoethyl)naphthalene deriv. which has a valuable pharmacological effect on central nervous system, anxiety remission, antipsychotic, pain relief, ovulation, hematogenous circuiation of brain, immune modulation and the like. CONSTITUTION: This novel deriv ...


5
Mansour Hamid A, Taverne Thierry, Houssin Raymond, Lesieur Isabelle, Depreux Patrick, Adam Gerard, Caignard Daniel Henri, Renard Pierre, Rettori Marie Claire: Novel aminoalkyl benzothiazolinones, production thereof, and pharmaceutical composition containing the compounds. Adir, October 9, 1995: JP1995-258237

PURPOSE: To provide the subject novel compound having high affinity and selectivity with respect to sigma receptors, useful for prevention and treatment of neurological diseases, depression, anxiety, acute or chronic arthritis or the like. CONSTITUTION: This compound is represented by formula I {whe ...