1
Hosztafi Sandor Dr, Makleit Sandor Dr, Szilagyi Laszlo Dr, Zsupan Kalman Dr: Morphinane-skeletoned hydrazone derivatives, process for preparing them, pharmaceutical composition and use.. Alkaloida Vegyeszeti Gyar, October 28, 1987: EP0242417-A1 (8 worldwide citation)

The present invention relates to novel morphinane-skeletoned compounds of the formula (I) the steric isomers and the pharmaceutically acceptable salts thereof, a novel process for producing the same and pharmaceutical compositions comprising the same as active ingredients. The novel compounds can be ...


2
Hosztafi Sandor Dr, Timar Tibor Dr, Nagy Geb Vajda Julianna, Fabian Geb Orban Ilona: Process for n-demethylating morphinane alkaloids.. Alkaloida Vegyeszeti Gyar, January 22, 1986: EP0168686-A1 (2 worldwide citation)

1. Process for the preparation of compounds having the N-demethylmorphinane structure of the general formula (III) see diagramm : EP0168686,P8,F1 wherein Z is CH2 -CH2 or CH=CH, Y is an oxygen atom or a group R3 and R4 wherein R3 is a hydrogen atom, a hydroxy group, an acyloxy group having from 1 to ...