1
Osamu Asano, Hitoshi Harada, Yorihisa Hoshino, Seiji Yoshikawa, Takashi Inoue, Tatsuo Horizoe, Nobuyuki Yasuda, Kaya Nagata, Junsaku Nagaoka, Manabu Murakami, Seiichi Kobayashi: Purine derivatives and adenosine A2 receptor antagonists serving as preventives/remedies for diabetes. Eisai, Birch Stewart Kolasch & Birch, June 17, 2003: US06579868 (65 worldwide citation)

The present invention provides a preventive or therapeutic agent of a new type for diabetes mellitus and diabetic complications on the basis of an adenosine A2 receptor antagonistic action.


2
Mineo Watanabe, Hitoshi Harada, Masanori Takemura: Method for manufacturing wafer. Mitsubishi Materials Corporation, Mitsubishi Materials Silicon Corporation, Scully Scott Murphy & Presser, July 4, 1995: US05429711 (53 worldwide citation)

There is disclosed a wafer-manufacturing method in which a single crystal ingot is first sliced into a plurality of wafers, and both surfaces of each wafer are subjected to grinding or lapping operation. Then, the front and back surfaces of the wafer are subjected to etching. Thereafter, the back su ...


3
Hitoshi Harada, Masato Ueda, Yoshihiko Kotake, Masahiro Yasuda, Daisuke Iida, Junichi Nagakawa, Makoto Nakagawa: Pyrimidine compound and medicinal composition thereof. Eisai R&D Management, Birch Stewart Kolasch & Birch, July 8, 2008: US07396836 (50 worldwide citation)

A compound having excellent adenosine receptor (A1, A2A, A2B receptor) antagonistic action, of the following formula, a salt thereof or a solvate of them: wherein, R1 and R2, same or different, each represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a ...


4
Hitoshi Harada, Yasumi Ohsera: Heat radiating insulation for coil. Nippondenso, Cushman Darby & Cushman, November 25, 1986: US04624884 (36 worldwide citation)

A thermosetting synthetic resin composition consisting mainly of, for example, an epoxy resin is melted at a temperature of 70.degree. to 130.degree. C. After adding a filler to the resin composition, the resultant mixture is kneaded and rapidly cooled. The composition consists of a thixotropy agent ...


5
Nobuo Kyougoku, Hitoshi Harada: Food vessel using heating element for microwave oven. Suntory, Bachman & LaPointe, November 21, 1989: US04882463 (32 worldwide citation)

A food vessel comprising a heating element for use in a household microwave oven is provided. The heating element is made of paper and a dielectric material such as aluminum foil. When bread dough or so forth is put into the vessel to be heated in the microwave oven, temperature of the heating eleme ...


6
Masanobu Shinoda, Eita Emori, Fumiyoshi Matsuura, Toshihiko Kaneko, Norihito Ohi, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Sadakazu Miyashita, Taro Hibara, Takashi Seiki, Richard Clark, Hitoshi Harada: Carboxylic acid derivatives and drugs containing the same. Eisai, Birch Stewart Kolasch & Birch, April 26, 2005: US06884821 (23 worldwide citation)

Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R1 is hydrogen, hydroxyl, alkyl, or the like; L is a sin ...


7
Osamu Asano, Hitoshi Harada, Seiji Yoshikawa, Nobuhisa Watanabe, Takashi Inoue, Tatsuo Horizoe, Nobuyuki Yasuda, Kaya Ohashi, Hiroe Minami, Junsaku Nagaoka, Manabu Murakami, Seiichi Kobayashi, Isao Tanaka, Tsutomu Kawata, Naoyuki Shimomura, Hiroshi Akamatsu, Naoki Ozeki, Toshikazu Shimizu, Kenji Hayashi, Toyokazu Haga, Shigeto Negi, Toshihiko Naito: Condensed imidazole compounds and a therapeutic agent for diabetes mellitus. Eisai, Birch Stewart Kolasch & Birch, January 11, 2005: US06841549 (19 worldwide citation)

The present invention provides a preventive or therapeutic agent for diabetes mellitus and diabetic complications, which is a new type based on an adenosine A2 receptor antagonist action. That is, it provides a novel condensed imidazole compound which has an adenosine A2 receptor antagonist action, ...


8
Yoshihiro Taki, Susumu Miyakawa, Hajime Akado, Hitoshi Harada, Satoshi Inukai, Atsushi Sakaida: Zig zag filter element. Nippon Denso, April 19, 1988: US04738778 (12 worldwide citation)

The filter element of the present has a plurality of wavy portions which are so arranged that a plurality of wavy portions make a generally ring like structure. In order to reduce the pressure drop when the fluid flows through the filter element, the present filter element has a special shaped radia ...


9
Hitoshi Harada, Osamu Asano, Shuhei Miyazawa, Masato Ueda, Masahiro Yasuda, Nobuyuki Yasuda: 2-aminopyridine compounds and use thereof as drugs. Eisai, Birch Stewart Kolasch & Birch, June 15, 2004: US06750232 (10 worldwide citation)

A class of substituted compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by formula (II), wherein R


10
Chikato Ninagawa, Tadashi Ozaki, Minoru Yonekawa, Hitoshi Harada: Aluminium alloy cylinder and manufacturing method thereof. Kioritz Corporation, Karl W Flocks, September 9, 1980: US04221639 (9 worldwide citation)

An aluminium alloy cylinder includes a cylinder body and a cylinder bore therein. An iron layer is electrodeposited on the wall surface of the cylinder bore by means of a high cathode current density so that a multiplicity of randomly oriented channels are formed in the electrodeposited iron layer.