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Shimesu Motoyama, Satashi Sato, Seiichi Umeda, Hirotsune Yasumi, Emiko Suto, Yuko Takasaka, Takuichi Tsujino: Process for the preparation of activated pharmaceutical compositions. Freund Industry Company, Oblon Fisher Spivak McClelland & Maier, September 10, 1985: US04540602 (130 worldwide citation)

Disclosed is a process for the preparation of an activated pharmaceutical composition containing a solid drug that is scarcely soluble in water, the pharmaceutical composition being characterized in that, when it is administered orally, the drug is readily absorbed to attain its high blood concentra ...


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Shimesu Motoyama, Shizuka Sakashita, Nagayoshi Myo, Hirotsune Yasumi, Hiroaki Ogishima: Coating method and apparatus. Freund Industrial, Kane Dalsimer Kane Sullivan and Kurucz, June 3, 1986: US04592302 (21 worldwide citation)

Coating method and apparatus, in which jet streams of a high-pressure fluid are ejected in the opposed directions into a pulverization zone in a pulverizer to hit a raw material conveyed by one of the jet streams on the other and thereby pulverize the same, the surfaces of particles of the resultant ...


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Kazuomi Unosawa, Shigemi Isobe, Takerou Adachi, Hirotsune Yasumi, Kouji Fukuda, Naoya Watanabe: Spray gun. FREUND CORPORATION, Wenderoth Lind & Ponack L, July 7, 2015: US09073077

A spray gun (1) forms a desired spray pattern by atomizing by means of atomizing air (A) a spray liquid which is sprayed from a liquid ejection port (44) opened/closed by a needle valve (4), and jetting pattern air (P) to the flow of spray mist of the atomized spray liquid. A nozzle taper angle (θ1) ...


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Hirotsune Yasumi, Masaru Ohmae: Highly Water Dispersible Powder and Production Method Thereof. Freund Corporation, Hoffmann & Baron, February 11, 2010: US20100034956-A1

Provided is a highly water dispersible powder which exhibits a high water dispersibility in spite of the inclusion of a poorly water soluble component, and maintains the high water dispersibility stably over time. The highly water dispersible powder includes a poorly water soluble component, a water ...


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Kazuomi Unosawa, Shigemi Isobe, Takerou Adachi, Hirotsune Yasumi, Kouji Fukuda, Naoya Watanabe: Spray gun. Chevron USA, The Regents of the University of California, September 20, 2012: US20120234942-A1

A spray gun (1) forms a desired spray pattern by atomizing by means of atomizing air (A) a spray liquid which is sprayed from a liquid ejection port (44) opened/closed by a needle valve (4), and jetting pattern air (P) to the flow of spray mist of the atomized spray liquid. A nozzle taper angle (θ1) ...