1
Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Takashi Sonobe, Satoru Yoneya, Chiharu Sone: Sustained release pharmaceutical composition of solid medical material. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, September 13, 1983: US04404183 (106 worldwide citation)

Sustained release pharmaceutical compositions of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl ...


2
Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Takashi Sonobe, Satoru Yoneya, Chiharu Sone: Sustained release pharmaceutical composition of solid medical material. Yamanouchi Pharmaceutical, Burgess Ryan and Wayne, August 10, 1982: US04343789 (102 worldwide citation)

Sustained release pharmaceutical composition of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl ...


3
Hiroitsu Kawata, Tadayoshi Ohmura, Katsuhiko Yano, Mikio Matsumura, Saburo Higuchi, Yoshiaki Soeishi: Nifedipine-containing solid preparation composition. Yamanouchi Pharmaceutical, Sprung Horn Kramer & Woods, November 1, 1983: US04412986 (82 worldwide citation)

A novel nifedipine-containing solid pharmaceutical preparation composition comprising a mixture of nifedipine and at least one 1st(a) substance selected from polyvinyl pyrrolidone, methyl cellulose, hydroxypropyl cellulose and hydroxypropylmethyl cellulose; a mixture of nifedipine, at least one 1st( ...


4
Yutaka Konno, Hiroitsu Kawata, Masayoshi Aruga, Takashi Sonobe, Mitsuo Mitomi: Patch. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, August 11, 1987: US04685911 (76 worldwide citation)

A patch having good transdermal property which utilizes a suppository base e.g. triglyceride of a vegetable saturated fatty acid having 12 to 18 carbon atoms together with a penetration enhancer.


5
Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Takashi Sonobe, Satoru Yoneya, Chiharu Sone: Sustained release pharmaceutical composition of solid medical material. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, June 16, 1987: US04673564 (49 worldwide citation)

Sustained release pharmaceutical compositions of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl ...


6
Muneo Fukui, Yutaka Konno, Yukio Kubota, Masayoshi Aruga, Hiroitsu Kawata: Solid drug preparations. Yamanouchi Pharmaceutical, Burgess Ryan and Wayne, April 19, 1983: US04380534 (38 worldwide citation)

A solid microdose drug preparation containing a microdose drug such as formoterol fumarate or .beta.-methyldigoxin coated with wax.


7
Yutaka Konno, Hiroitsu Kawata, Masayoshi Aruga, Takashi Sonobe, Mitsuo Mitomi: Patch. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, November 7, 1989: US04879119 (29 worldwide citation)

A patch having good transdermal property which utilizes a suppository base e.g. triglyceride of a vegetable saturated fatty acid having 12 to 18 carbon atoms together with a penetration enhancer.


8
Yutaka Konno, Hiroitsu Kawata, Masayoshi Aruga, Takashi Sonobe, Mitsuo Mitomi: Transdermal formulation of nicardipine hydrochloride. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, January 20, 1987: US04637930 (21 worldwide citation)

A formulation is provided for the transdermal administration of nicardipine hydrochloride. The formulation is comprised of nicardipine hydrochloride dissolved or suspended in a mixed liquid composed of an urea and at least one compound selected from the group consisting of propylene glycol, a monohy ...


9
Hiroitsu Kawata, Tadayoshi Ohmura, Shunji Hasumi, Yutaka Konno, Masayoshi Aruga, Seiki Tashiro, Toshimitsu Konno, Ken Iwai: Oily compositions of antitumor drugs. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, March 25, 1986: US04578391 (13 worldwide citation)

An oily composition of an antitumor drug comprising at least one sparingly oil soluble or water-soluble antitumor drug, at least one fat or oil, and at least one solubilizing adjuvant in an oily vehicle selected from the group consisting of crown ether, lecithin, polyethylene glycol, propylene glyco ...


10
Kenichi Muraoka, Yoichi Setoguchi, Tadamasa Kawase, Hiroitsu Kawata, Hisamoto Komatsu, Makoto Uchida: Granular composition of difficult digestible polysaccharides. Yamanouchi Pharmaceutical, Burgess Ryan and Wayne, November 17, 1987: US04707376 (11 worldwide citation)

A granular composition of difficultly digestible polysaccharides (dietary fiber) is composed of a combination of one or more difficultly digestible polysaccharides selected from polysaccharides derived from roots of the plant such as glucomannan, polysaccharides derived from fruits of plants such as ...



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