1
Henry Laurent, Dieter Bittler, Sybille Beier, Walter Elger: Estriol esters. Schering Aktiengesellschaft, Millen & White, April 19, 1988: US04738957 (31 worldwide citation)

Estriol esters of Formula I ##STR1## wherein R is, in each case, the residue of an aliphatic monocarboxylic acid of 3-10 carbon atoms,


2
Ralph Lipp, Henry Laurent, Clemens Gunther, Jutta Riedl, Peter Esperling, Ulrich Tauber: Agent for transdermal administration that contains gestodene esters. Schering Aktiengesellschaft, January 12, 1999: US05858394 (23 worldwide citation)

An agent for transdermal administration is described, which is characterized in that it contains gestodene esters with 1 to 20 carbon atoms in the ester radical optionally in combination with one or two estrogen(s).


3
Guenter Neef, Gerhard Sauer, Rudolf Wiechert, Helmut Hofmeister, Ralph Rohde, Klaus Annen, Henry Laurent, Sybille Beier, Wolfgang Losert, Walter Elger, David Henderson: 11.beta.-aryl estradienes, processes for their production and pharmaceutical preparations containing them. Schering Aktiengesellschaft, Millen & White, August 20, 1985: US04536401 (22 worldwide citation)

Compounds of the formula I ##STR1## wherein R.sub.1 is ##STR2## wherein R.sup.I and R.sup.II each independently is alkyl of 1-4 carbon atoms, or R.sup.I and R.sup.II together with the connecting N-atom form a 5- or 6-membered heterocyclic ring whose remaining atoms are all C-atoms, or which also inc ...


4
Klaus Annen, Henry Laurent, Helmut Hofmeister, Rudolf Wiechert, Hans Wendt: 6.alpha.-methyl corticoids, their production and use. Schering Aktiengesellschaft, Millen & White, February 24, 1987: US04645763 (15 worldwide citation)

6.alpha.-Methyl corticoids of formula I ##STR1## wherein is a single bond or a double bond, R is acyloxy of up to 8 carbon atoms, and X is chlorine, hydroxy, or acyloxy of up to 8 carbon atoms, are pharamacologically effective substances.


5
Helmut Hofmeister, Rudolf Wiechert, Klaus Annen, Henry Laurent, Hermann Steinbeck: .DELTA..sup.15 -Steroids and pharmaceutical compositions thereof. Schering Aktiengesellschaft, Millen & White, March 28, 1978: US04081537 (14 worldwide citation)

.DELTA..sup.15 -Steroids of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, trialkylsilyl or acyl; R.sub.2 is ethynyl, chloroethynyl or propinyl; and X is an oxygen atom, ##STR2## or NOR.sub.4 wherein R.sub.3 is a hydrogen atom or acyl and R.sub.4 is a hydrogen atom, acyl, alkyl or tetrahyd ...


6
Henry Laurent, Rudolf Wiechert: 17.alpha.-alkyl-17.beta.-hydroxy-1.alpha.-methyl-4-androsten-3-ones, their production and use pharmaceutically. Schering Aktiengesellschaft, Millen & White, June 16, 1987: US04673673 (13 worldwide citation)

17.alpha.-Alkyl-17.beta.-hydroxy-1.alpha.-methyl-4-androsten-3-ones of the formula ##STR1## wherein R is a straight-chain alkyl residue of 3-8 carbon atoms, i.e., C.sub.3-8 -n-alkyl, are pharmacologically active compounds distinguished by antiandrogenic activity, especially upon topical application.


7
Henry Laurent, Peter Esperling, Kurt Hamp, Herbert Schneider, Helmut Wachtel: Chiral phenyldihydrofuranones as PDE-IV inhibitors. Schering Aktiengesellschaft, Millen White Zelano & Branigan, January 4, 2000: US06011060 (12 worldwide citation)

Described are racemic and enantiomerically pure chiral phenyldihydrofuranones, their preparation and their use in drugs (selective inhibition of the cAMP-specific phosphodiesterase IV).


8

9
Karl Petzoldt, Henry Laurent, Rudolf Wiechert: 3.beta.,7.beta.,15.alpha.-Trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and their preparation. Schering Aktiengesellschaft, Millen & White, March 6, 1984: US04435327 (11 worldwide citation)

A process for the preparation of 3.beta.,7.beta.,15.alpha.-trihydroxy-5-androsten-17-one and the 3,15-dipivalate thereof comprises epimerizing 3.beta.,7.alpha.,15.alpha.-trihydroxy-5-androsten-17-one in the presence of a ketone with or without a solvent, with dilute mineral acid and subsequent treat ...


10
Henry Laurent, Eckhard Ottow, Gerald Kirsch, Helmut Wachtel, Herbert Schneider, Daryl Faulds, Harald Dinter: Chiral methylphenyloxazolidinones. Schering Aktiengesellschaft, Millen White Zelano Branigan P C, February 15, 2000: US06025376 (10 worldwide citation)

This invention relates to (R)-(-)-methylphenyloxazolidinone derivatives, a process for their production and their use as pharmaceutical agents.