Henry Laurent, Dieter Bittler, Sybille Beier, Walter Elger: Estriol esters. Schering Aktiengesellschaft, Millen & White, April 19, 1988: US04738957 (31 worldwide citation)

Estriol esters of Formula I ##STR1## wherein R is, in each case, the residue of an aliphatic monocarboxylic acid of 3-10 carbon atoms,

Ralph Lipp, Henry Laurent, Clemens Gunther, Jutta Riedl, Peter Esperling, Ulrich Tauber: Agent for transdermal administration that contains gestodene esters. Schering Aktiengesellschaft, January 12, 1999: US05858394 (23 worldwide citation)

An agent for transdermal administration is described, which is characterized in that it contains gestodene esters with 1 to 20 carbon atoms in the ester radical optionally in combination with one or two estrogen(s).

Guenter Neef, Gerhard Sauer, Rudolf Wiechert, Helmut Hofmeister, Ralph Rohde, Klaus Annen, Henry Laurent, Sybille Beier, Wolfgang Losert, Walter Elger, David Henderson: 11.beta.-aryl estradienes, processes for their production and pharmaceutical preparations containing them. Schering Aktiengesellschaft, Millen & White, August 20, 1985: US04536401 (22 worldwide citation)

Compounds of the formula I ##STR1## wherein R.sub.1 is ##STR2## wherein R.sup.I and R.sup.II each independently is alkyl of 1-4 carbon atoms, or R.sup.I and R.sup.II together with the connecting N-atom form a 5- or 6-membered heterocyclic ring whose remaining atoms are all C-atoms, or which also inc ...

Klaus Annen, Henry Laurent, Helmut Hofmeister, Rudolf Wiechert, Hans Wendt: 6.alpha.-methyl corticoids, their production and use. Schering Aktiengesellschaft, Millen & White, February 24, 1987: US04645763 (15 worldwide citation)

6.alpha.-Methyl corticoids of formula I ##STR1## wherein is a single bond or a double bond, R is acyloxy of up to 8 carbon atoms, and X is chlorine, hydroxy, or acyloxy of up to 8 carbon atoms, are pharamacologically effective substances.

Helmut Hofmeister, Rudolf Wiechert, Klaus Annen, Henry Laurent, Hermann Steinbeck: .DELTA..sup.15 -Steroids and pharmaceutical compositions thereof. Schering Aktiengesellschaft, Millen & White, March 28, 1978: US04081537 (14 worldwide citation)

.DELTA..sup.15 -Steroids of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, trialkylsilyl or acyl; R.sub.2 is ethynyl, chloroethynyl or propinyl; and X is an oxygen atom, ##STR2## or NOR.sub.4 wherein R.sub.3 is a hydrogen atom or acyl and R.sub.4 is a hydrogen atom, acyl, alkyl or tetrahyd ...

Henry Laurent, Rudolf Wiechert: 17.alpha.-alkyl-17.beta.-hydroxy-1.alpha.-methyl-4-androsten-3-ones, their production and use pharmaceutically. Schering Aktiengesellschaft, Millen & White, June 16, 1987: US04673673 (13 worldwide citation)

17.alpha.-Alkyl-17.beta.-hydroxy-1.alpha.-methyl-4-androsten-3-ones of the formula ##STR1## wherein R is a straight-chain alkyl residue of 3-8 carbon atoms, i.e., C.sub.3-8 -n-alkyl, are pharmacologically active compounds distinguished by antiandrogenic activity, especially upon topical application.

Henry Laurent, Peter Esperling, Kurt Hamp, Herbert Schneider, Helmut Wachtel: Chiral phenyldihydrofuranones as PDE-IV inhibitors. Schering Aktiengesellschaft, Millen White Zelano & Branigan, January 4, 2000: US06011060 (12 worldwide citation)

Described are racemic and enantiomerically pure chiral phenyldihydrofuranones, their preparation and their use in drugs (selective inhibition of the cAMP-specific phosphodiesterase IV).


Karl Petzoldt, Henry Laurent, Rudolf Wiechert: 3.beta.,7.beta.,15.alpha.-Trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and their preparation. Schering Aktiengesellschaft, Millen & White, March 6, 1984: US04435327 (11 worldwide citation)

A process for the preparation of 3.beta.,7.beta.,15.alpha.-trihydroxy-5-androsten-17-one and the 3,15-dipivalate thereof comprises epimerizing 3.beta.,7.alpha.,15.alpha.-trihydroxy-5-androsten-17-one in the presence of a ketone with or without a solvent, with dilute mineral acid and subsequent treat ...

Henry Laurent, Eckhard Ottow, Gerald Kirsch, Helmut Wachtel, Herbert Schneider, Daryl Faulds, Harald Dinter: Chiral methylphenyloxazolidinones. Schering Aktiengesellschaft, Millen White Zelano Branigan P C, February 15, 2000: US06025376 (10 worldwide citation)

This invention relates to (R)-(-)-methylphenyloxazolidinone derivatives, a process for their production and their use as pharmaceutical agents.