1
Stephen N Cozzette, Graham Davis, Jeanne A Itak, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Susan J Steiner, Paul Van Der Werf, Henry J Wieck: Wholly microfabricated biosensors and process for the manufacture and use thereof. I Stat Corporation, Pennie & Edmonds, April 6, 1993: US05200051 (651 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


2
Imants R Lauks, Henry J Wieck, Michael P Zelin, Philip Blyskal: Disposable sensing device for real time fluid analysis. I Stat Corporation, Pennie & Edmonds, March 17, 1992: US05096669 (537 worldwide citation)

A system comprising a disposable device and hand held reader can perform a variety of electrochemical measurements on blood or other fluids. In operation, a fluid sample is drawn into the disposable device through an orifice by capillary action. The orifice is sealed off and the disposable device is ...


3
Stephen N Cozzette, Graham Davis, Jeanne Itak, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Susan Steiner, Paul Van Der Werf, Henry J Wieck: Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor. I Stat Corporation, Pennie & Edmonds, November 5, 1991: US05063081 (500 worldwide citation)

A plurality of uniform microfabricated sensing devices are produced by establishing a plurality of base sensors on a substrate wafer, forming over at least a portion of each base sensor a permselective layer, superimposing a photoformable proteinaceous photoresist layer over a substantial portion of ...


4
Stephen N Cozzette, Graham Davis, Imants R Lauks, Randall M Mier deceased, Sylvia Piznik, Nicolaas Smit, Paul Van Der Werf, Henry J Wieck, Susan Steiner, Jeanne Itak: Process for the manufacture of wholly microfabricated biosensors. i STAT Corporation, Pennie & Edmonds, November 17, 1998: US05837454 (356 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


5
Stephen N Cozzette, Graham Davis, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Paul Van Der Werf, Henry J Wieck: Process for the manufacture of wholly microfabricated biosensors. i Stat Corporation, Pennie & Edmonds, September 10, 1996: US05554339 (303 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


6
Stephen N Cozzette, Graham Davis, Lisa A Holleritter, Imants R Lauks, Sylvia Piznik, Nicolaas J Smit, Jody A Tirinato, Henry J Wieck, Michael P Zelin: Method for analytically utilizing microfabricated sensors during wet-up. I Stat Corporation, Pennie & Edmonds, May 12, 1992: US05112455 (220 worldwide citation)

A method of determining the concentration of a preselected analyte species present in a sample fluid is disclosed, which method comprises: (a) providing an external computational means, a reference electrode and at least one substantially dry-stored sensor capable of exhibiting a response to changes ...


7
Henry J Wieck, Paul C Dahlstrom, Dennis W Nixon: Non-contract method for assay reagent volume dispense verification. Chiron Corporation, James E Austin, David P Lentini, Robert P Blackburn, August 1, 2000: US06097831 (149 worldwide citation)

Methods and systems for verifying the volume of a reagent dispensed into an affinity assay vessel are described. In one embodiment, a method is for verifying the volume of a reagent dispensed into an affinity assay vessel described in which a fluid sample is deposited into a vessel that includes a r ...


8
Stephen N Cozzette, Graham Davis, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Paul Van Der Werf, Henry J Wieck: Process for the manufacture of wholly microfabricated biosensors. i Stat Corporation, Pennie & Edmonds, November 14, 1995: US05466575 (140 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


9
Imants R Lauks, Henry J Wieck: Method and apparatus for testing chemical and ionic sensors. Integrated Ionics, Pennie & Edmonds, September 5, 1989: US04864229 (126 worldwide citation)

A method and apparatus for automatically testing chemical and ionic sensing electronic circuits is provided. A fluid used in testing is placed in a hollow pipette with at least one open end. The open end of the pipette is applied directly against a sensing layer on the sensing electronic circuit for ...


10
Stephen N Cozzette, Graham Davis, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Paul Van der Werf, Henry J Wieck: Methods for microdispensing patterened layers. i STAT Corporation, Pennie & Edmonds, October 23, 2001: US06306594 (96 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...