1
Roland Reiner, Helmut Heide, Kari Koster: Anchorage for highly stressed endoprostheses. Battelle Institut e V, Fisher Christen & Sabol, May 13, 1980: US04202055 (127 worldwide citation)

An implantable prosthesis anchorage which contains a non-porous outer coating in the regions which is positioned in contact with bone. The non-porous outer coating consists of (i) at least one bioactive resorbable ceramic material which is a calcium phosphate and (ii) at least one polymer which is m ...


2
Helmut Heide, Eva Poeschel, Ulrich Roth: Implantable bone replacement materials based on calcium phosphate ceramic material in a matrix and process for the production thereof. Battelle Institut e V, Fisher Christen & Sabol, January 5, 1982: US04309488 (114 worldwide citation)

An implantable bone replacement material (body) based on completely or partially resorbable particles incorporated in a matrix material. The particles are composed of bioactive sintered calcium phosphate ceramic material having a CaO:P.sub.2 O.sub.5 composition ratio between 3:1 and 4:1. The replace ...


3
Heinrich Deibig, Helmut Heide, Roland Reiner, Kari Koster: Bone replacement or prosthesis anchoring material. Batelle Institut e V, Fisher Christen & Sabol, March 11, 1980: US04192021 (107 worldwide citation)

Bone replacement or prosthesis anchoring material on the basis of sintered calcium phosphates which consists of a mixture of calcium phosphates with low or high-molecular-weight organic substances. More specifically, the anchoring material consists of a mixture of calcium phosphates composed of CaO ...


4
Roland Reiner, Wolfgang KiBing, Helga Doring, Kari Koster Losche, Helmut Heide: Implantable drug depot and process for the production thereof. Battelle Institut e V, Fisher Christen & Sabol, March 30, 1982: US04322398 (50 worldwide citation)

An implantable drug depot for the treatment of diseases of the bone or bone marrow. The depot consisting of a matrix in which at least one active ingredient is incorporated and contains at least one adjuvant agent to control the kinetics of the drug release. The matrix material consists of resorbabl ...


5
Guido Riess, Helmut Heide, Roland Reiner, Kari Koster, Gunther Brotz: Artificial tooth with implantable tooth root. Guido Reiss, Scully Scott Murphy & Presser, December 18, 1979: US04178686 (47 worldwide citation)

An artificial tooth with an implantable root adapted to permanently grow together with the jawbone and, also under high mechanical loads as is the case for natural teeth, will not allow for the production of a rejection or repelling reaction between the natural bone and the implant. The tooth root i ...


6
Helmut Heide, Heinz Werner Etzkorn, Eva Poeschel, Helmut Steininger: Method of producing implantable bone replacement materials. Battelle Institute e V, Fisher Christen & Sabol, October 27, 1987: US04702930 (35 worldwide citation)

Metallic implants with a coating of hydroxyl apatite are described. Hot isostatic pressing permits pore-free compaction of the hydroxyl apatite layer and results in firm bonding of the layer on the metallic core. The surface of the layer is partially dehydrated by means of ion bombardment, and a bio ...


7
Helmut Heide, Joachim Pabst, Albrecht Dinkelaker, Olaf Pobantz: Resorbable bone replacement and bone formation material. curasan, Myers Bigel Sibley & Sajovec PA, March 14, 2006: US07012034 (25 worldwide citation)

The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous β-tricalcium phosphate (β-TCP).


8
Helmut Heide, Joachim Pabst, Albrecht Dinkelaker, Olaf Pobantz: Resorbable bone replacement and bone formation material. curasan, Myers Bigel Sibley & Sajovec PA, August 8, 2006: US07087540 (17 worldwide citation)

The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous β-tricalcium phosphate (β-TCP).


9
Helmut Heide, Ulrich Hoffmann, Gunther Brotz, Eva Poeschel: Process for producing catalyst supports or catalyst systems having open pores. Christen & Sabol, May 18, 1976: US03957685 (15 worldwide citation)

A process for producing ceramic, ceramic-metal or metal catalyst supports or catalysts with open, interconnecting pores. The process forming a dense agglomeration of spherical, cylindrical or similar bodies of generally uniform size. These bodies are connected together at their mutual contact points ...


10
Michael Paulista, Jens Pohl, Joachim Pabst, Helmut Heide: Compounds with improved cartilage-inducing and/or bone-inducing activity. Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka mbH, Rothwell Figg Ernst & Manbeck P C, April 29, 2008: US07365051 (9 worldwide citation)

The present invention concerns a bioactive implant material having a cartilage-inducing and/or bone-inducing activity composed of two components A and B, of which A is a bone-inducing and/or cartilage-inducing protein or protein mixture and preferably one or several proteins from the TGF-β superfami ...