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Heller Jorge, Baker Richard W: Bioerodible ocular device. Alza Corporation, Ciotti Thomas E, Mandell Edward L, Sabatine Paul L, May 21, 1974: US3811444 (103 worldwide citation)

An ocular insert for the continuous controlled administration of a predetermined therapeutically effective dosage of drug to the eye over a prolonged period of time. The insert comprises a drug formulation dispersed through a body of selected hydrophobic polycarboxylic acids which erode in the envir ...


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Saito Kenichiro, Heller Jorge, Skinner Wilfred A: Composition for percutaneously administering metoclopramide. Nitto Electric Ind Co, August 21, 1985: GB2153223-A (33 worldwide citation)

COMPOSITION POUR L'ADMINISTRATION PERCUTANEE DU METOCLOPRAMIDE; LA COMPOSITION DESTINEE A L'APPLICATION A LA PEAU D'UN MAMMIFERE EST CONSTITUEE DE METOCLOPRAMIDE DANS UN SYSTEME SUPPORT COMPRENANT AU MOINS UN ADJUVANT ET AU MOINS UN SOLVANT, L'ADJUVANT ETANT UN ESTER DE MONOALCOOL D'UN ACIDE MONOCAR ...


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Katz Martin, Nacht Sergio, Heller Jorge: System for transdermal drug delivery.. Advanced Polymer Systems, November 28, 1990: EP0399765-A2 (18 worldwide citation)

Transdermal drug delivery systems comprise a backing or enclosure having a matrix layer which incorporates a drug and a percutaneous enhancer for the drug. The percutaneous enhancer and/or drug will be contained within polymeric particles dispersed through the matrix layer, where the polymeric parti ...


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Shah Devang, Barr John, Baxter Brian, Heller Jorge: Base-stabilized polyorthoester formulations. Appharma, Shah Devang, Barr John, Baxter Brian, Heller Jorge, NGUYEN Sam L, November 22, 2007: WO/2007/133751 (6 worldwide citation)

A stabilized semi-solid delivery vehicle contains a polyorthoester and an excipient, and a pharmaceutical composition contains an active agent, optionally a stabilizing agent, and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is sui ...


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Saito Kenichiro, Heller Jorge, Skinner Wilfred A: Pharmaceutical compositions for percutaneous administration. Nitto Electric Ind Co, January 16, 1985: GB2142238-A (2 worldwide citation)

A pharmaceutical composition for administration to the skin comprises a pharmaceutical agent, such as a benzodiazepine, and a percutaneous carrier liquid comprising: (A) a compound melting at below 38 DEG C which is a C5-24 aliphatic hydrocarbon optionally halo- substituted, a C7-18 ester of an alip ...


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Ng Steven Y, Shen Hui Rong, Heller Jorge: Semi-solid delivery vehicle and pharmaceutical compositions. Ap Pharma, Ng Steven Y, Shen Hui Rong, Heller Jorge, NGUYEN Sam L, April 6, 2006: WO/2006/037116 (2 worldwide citation)

A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the a ...


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Shah Devang, Barr John, Baxter Brian, Heller Jorge: Formulations of 5-ht3 receptor antagonists with polyorthoester for use in the prevention of acute and delayed chemotherapy- induced nausea and vomiting (cinv). Ap Pharma, Shah Devang, Barr John, Baxter Brian, Heller Jorge, NGUYEN Sam L, November 22, 2007: WO/2007/133752 (2 worldwide citation)

A pharmaceutical composition for the sustained release of an effective amount of a selective 5-hydroxytryptamine 3 (5-HT3) receptor antagonist for the prevention, reduction or alleviation of acute and delayed chemotherapy-induced nausea and vomiting (CINV) following a course of emetogenic chemothera ...