1
Choi Ha Soon, Wang Zhicheng, Gray Nathanael Schiander, Gu Xiang Ju, He Xiaohui, He Yun, Jiang Tao, Liu Yi, Richmond Wendy, Sim Taebo, Yang Kunyong: Compounds and compositions as protein kinase inhibitors. Irm, Choi Ha Soon, Wang Zhicheng, Gray Nathanael Schiander, Gu Xiang Ju, He Xiaohui, He Yun, Jiang Tao, Liu Yi, Richmond Wendy, Sim Taebo, Yang Kunyong, REID Scott W, September 1, 2005: WO/2005/080393 (43 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


2
Ren Pingda, Wang Xia, Jiang Songchun, Nagle Advait, Okram Barun, He Yun, Xie Yongping, Wang Xing, Huang Shenlin, Wang Xiaodong, Liu Yi, Albaugh Pamela A, Gray Nathanael S, Zhang Guobao: Protein kinase inhibitors and methods for using thereof. Irm, Ren Pingda, Wang Xia, Jiang Songchun, Nagle Advait, Okram Barun, He Yun, Xie Yongping, Wang Xing, Huang Shenlin, Wang Xiaodong, Liu Yi, Albaugh Pamela A, Gray Nathanael S, Zhang Guobao, RAYMOND Daniel E, November 27, 2008: WO/2008/144253 (43 worldwide citation)

The invention provides compounds of formula (l) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the i ...


3
Ren Pingda, Zhang Guobao, You Shuli, Sim Taebo, Gray Nathanael, Xie Yongping, Wang Xing, He Yun: Compositions and methods for fgf receptor kinases inhibitors. Irm, Ren Pingda, Zhang Guobao, You Shuli, Sim Taebo, Gray Nathanael, Xie Yongping, Wang Xing, He Yun, SMITH Timothy L, November 29, 2007: WO/2007/136465 (33 worldwide citation)

Described are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or prevent disease or disordered associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activity of kinases such as ...


4
Pan Shifeng, Marsilje Thomas H, Lu Wenshuo, Gao Wenqi, Gray Nathanael Schiander, He Yun, Liu Yahua, Mi Yuan, Xie Yongping: Immunosuppressant compounds and compositions. Irm, Pan Shifeng, Marsilje Thomas H, Lu Wenshuo, Gao Wenqi, Gray Nathanael Schiander, He Yun, Liu Yahua, Mi Yuan, Xie Yongping, REID Scott W, September 9, 2005: WO/2005/082089 (24 worldwide citation)

The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particul ...


5
Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc, REID Scott W, May 4, 2006: WO/2006/047516 (17 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


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Albaugh Pamela A, He Yun, Jiang Songchun, Ren Pingda, Wang Xia, Wang Xing, Xie Yongping: [4,5]bipyrimidinyl-6,4-diamine derivatives as protein kinase inhbitors. Irm, Albaugh Pamela A, He Yun, Jiang Songchun, Ren Pingda, Wang Xia, Wang Xing, Xie Yongping, MCNALLY Lydia T, January 17, 2008: WO/2008/008747 (17 worldwide citation)

The invention provides a novel class of compounds of the Formula (I): in which the symbols have the meanings given in the description and claims, to pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abn ...


7
Ren Pingda, Wang Xia, He Yun, Okram Barun, Wang Xiaodong, Zhang Guobao, Liu Zuosheng, Liu Yi, Albaugh Pamela A: Pyrazolo [3,4-d] pyrimidines and 1, 2, 5, 6-tetraaza- as- indacenes as protein kinase inhibitors for cancer treatment. Irm, Ren Pingda, Wang Xia, He Yun, Okram Barun, Wang Xiaodong, Zhang Guobao, Liu Zuosheng, Liu Yi, Albaugh Pamela A, RAYMOND Daniel E, September 18, 2008: WO/2008/112695 (16 worldwide citation)

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provid ...


8
Sim Taebo, Nguyen Truc Ngoc, Wu Baogen, He Yun, Xie Yongping, Wang Xing, Zhang Guobao, Gray Nathanael S: Protein kinase inhibitors and methods for using thereof. Irm, Sim Taebo, Nguyen Truc Ngoc, Wu Baogen, He Yun, Xie Yongping, Wang Xing, Zhang Guobao, Gray Nathanael S, TONGCO WU Emily, December 24, 2008: WO/2008/157575 (15 worldwide citation)

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provid ...


9
He Yun, Ellis David Archer, Anaclerio Beth Marie, Kuhen Kelli L, Wu Baogen, Jiang Tao: Quinolones with anti-hiv activity. Irm, He Yun, Ellis David Archer, Anaclerio Beth Marie, Kuhen Kelli L, Wu Baogen, Jiang Tao, MANN Jeffry S, May 6, 2004: WO/2004/037853 (12 worldwide citation)

The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of proph ...


10
Chianelli Donatella, Cow Christopher, He Yun, Jiang Songchun, Li Xiaolin, Liu Xiaodong, Liu Zuosheng, Loren Jon, Molteni Valentina, Nabakka Juliet, Ren Pingda, Sim Taebo, Wang Xiaodong, You Shuli: Compositions and methods for modulating c-kit and pdgfr receptors. Irm, Chianelli Donatella, Cow Christopher, He Yun, Jiang Songchun, Li Xiaolin, Liu Xiaodong, Liu Zuosheng, Loren Jon, Molteni Valentina, Nabakka Juliet, Ren Pingda, Sim Taebo, Wang Xiaodong, You Shuli, TONGCO WU Emily, May 2, 2008: WO/2008/051757 (11 worldwide citation)

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention ...