1
Jaeschke Andres, Hausch Felix: Multiplex sequence variation analysis of dna samples by mass spectrometry. Bruker Saxonia Analytik, October 4, 2001: EP1138782-A2 (72 worldwide citation)

The invention relates to the simultaneous analysis of variations in distinct nucleic acid sequences within a complex nucleic acid mixture. The invention consists in the use of chips with spatially separated fields of photocleavable oligonucleotide probes which are commonly processed together with th ...


2
Kostrzewa Markus, Froehlich Thomas, Wenzel Thomas, Jaeschke Andreas, Hausch Felix: Mutation analysis by mass spectrometry using photolytically cleavable primers. Bruker Saxonia Analytik, August 28, 2002: EP1234888-A2 (67 worldwide citation)

The invention relates to a method of a mass-spectrometric analysis of known mutation sites in the genome, such as single nucleotide polymorphisms (SNPs), using the method of restricted primer extension. The invention consists of the use of primers with a photocleavable linker. The linker creates a g ...


3
HAUSCH FELIX, MAERZ ANDREAS M, BRACHER ANDREAS: [fr] Analogue de rapamycine spécifique au sous-type de FKBP à utiliser dans le traitement des maladies, [de] FKBP-subtypspezifisches Rapamycin-Analogon zur Verwendung bei der Behandlung von Erkrankungen, [en] FKBP subtype-specific rapamycin analogue for use in treatment of diseases. MAX PLANCK GESELLSCHAFT, May 8, 2013: EP2589383-A1 (1 worldwide citation)

[en] The present invention is directed to a FKBP subtype-specific rapamycin analogue selective for a single FKBP, wherein the FKBP subtype-specific rapamycin analogue preferentially forms a complex with only a single FKBP and this complex binds and/or inhibits the mammalian target of rapamycin for u ...


4
HAUSCH FELIX, GRAY GARY, SHAN LU, KHOSLA CHAITAN: Enzyme treatment of foodstuffs for celiac sprue, Enzymbehandlung von Nahrungsmitteln für Zöliakie, Traitement denzyme daliments pour maladie c liaque. UNIV LELAND STANFORD JUNIOR, January 25, 2012: EP2409711-A1 (1 worldwide citation)

Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.


5
Hausch Felix, Gray Gary, Shan Lu, Khosla Chaitan: Enzyme treatment of foodstuffs for celiac sprue. The Board Of Trustees Of The Leland Stanford Junior University, Hausch Felix, Gray Gary, Shan Lu, Khosla Chaitan, SHERWOOD Pamela J, August 21, 2003: WO/2003/068170 (1 worldwide citation)

Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.


6
Sollid Ludvig M, Hausch Felix, Gray Gary, Shan Lu, Kim Chu Young, Khosla Chaitan, Quarsten Hanne: Drug therapy for celiac sprue. The Board Of Trustees Of The Leland Stanford Junior University, Sollid Ludvig M, Hausch Felix, Gray Gary, Shan Lu, Kim Chu Young, Khosla Chaitan, Quarsten Hanne, SHERWOOD Pamela J, November 27, 2003: WO/2003/096984 (1 worldwide citation)

Celiac Sprue and/or dermatitis herpetiformis are treated by interfering with HLA binding of immunogenic gluten peptides. The antigenicity of gluten oligopeptides and the ill effects caused by an immune response thereto are decreased by administration of an HLA-binding peptide inhibitor. Such inhibit ...


7
Hausch Felix, Perez Balderas Francisco: Screening method for gpcr ligands. Max Planck Gesellschaft Zur Förderung Der Wissenschaften Ev, Hausch Felix, Perez Balderas Francisco, VOSSIUS Siebertstrasse 4 81675 Munich, February 28, 2008: WO/2008/022716 (1 worldwide citation)

This invention relates to a method of identifying a compound capable of binding to a target domain of a G-protein coupled receptor comprising the steps of: (a) providing a receptor comprising said target domain and a first group linked to said target domain; (b) bringing into contact said receptor o ...


8
HAUSCH FELIX, GRAY GARY, SHAN LU, KHOSLA CHAITAN: Enzyme treatment of foodstuffs for celiac sprue, Enzymbehandlung von Nahrungsmitteln für Zöliakie, Traitement denzyme de produits alimentaires pour maladie c liaque. UNIV LELAND STANFORD JUNIOR, September 14, 2011: EP2364718-A1

Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.


9
Frauendorf Christian Dr, Hausch Felix Dr, Klussmann Sven Dr, Lichte Andrea Dr: Methods for labeling l-nucleic acids. Noxxon Pharma, March 5, 2003: EP1288309-A1

Labeling (M1) L-nucleic acid (I) comprising preparing a part (P1) of (I); labeling P1 and ligating the labeled product to a second part (P2) of (I), prepared separately, is new. Independent claims are also included for: (1) L-nucleic acid (Ia) having a label that is attached to a non-terminal nucleo ...


10
WANG YANSONG, HAUSCH FELIX: [fr] Aza-amides bicycliques pour le traitement de troubles psychiatriques, [de] Bizyklische Aza-Amide zur Behandlung psychischer Erkrankungen, [en] Bicyclic aza-amides for treatment of psychiatric disorders. MAX PLANCK GESELLSCHAFT, January 29, 2014: EP2690102-A1

[en] The present invention relates to compounds of formula (I) having a bicyclic aza-amides scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or di ...