1
Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazoles, drugs containing these compounds and process for their preparation.. Thomae Dr K, October 17, 1990: EP0392317-A2 (78 worldwide citation)

The invention relates to benzimidazoles of the formula in which R1 to R6 are defined as in claim 1, their 1- and 3-isomer mixtures and their acid addition salts, which have useful properties. The novel compounds are in particular angiotensin II antagonists.


2
Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazol, medicaments containing them and process for their preparation.. Thomae Dr K, September 9, 1992: EP0502314-A1 (45 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of the 1 and 3 isomers thereof, and the salts thereof, which have valuable properties. The compounds are, in particular, angiotensin antagonists.


3
Bomhard Andreas Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Kobinger Walter Prof Dr, Lillie Christian Dr: Heteroaromatic amine derivatives, medicaments containing them and process for their preparation.. Thomae Dr K, December 10, 1986: EP0204349-A2 (33 worldwide citation)

Die vorliegende Erfindung betrifft neue heteroaromatische Aminderivate der allgemeinen Formel in der A eine -CH2-CH2-, -CH=CH- oder -C?2-CO-Gruppe und B eine Methylen-, Carbonyl- oder Thiocarbonylgruppe oder und B eine Methylengruppe, wobei das mit x gekennzeichnete Kohlenstoffatom jeweils mit dem P ...


4
Narr Berthold Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr, Entzeroth Michael Dr, Ries Uwe Dr: Benzimidazoles, medicaments containing them and process for their preparation.. Thomae Dr K, January 29, 1992: EP0468470-A1 (31 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of their 1-, 3-isomers, and their salts, which have valuable properties. The novel compounds are, in particular, angiotensin antagonists.


5
Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Lillie Christian Dr, Kobinger Walter Prof Dr, Dammgen Jurgen Dr: Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation.. Thomae Dr K, November 30, 1988: EP0292840-A2 (30 worldwide citation)

Cyclic amine derivatives of the formula in which A, B, E, G, R, R1, R2, m and n are as defined in Claim 1, their enantiomers, their diastereomers, their N-oxides and their acid addition salts have useful pharmacological properties, in particular a bradycardic action. The novel compounds can be prepa ...


6
Mueller Erich Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Van Meel Jacques Dr, Diederen Willi Dr: 2-aryl imidazoles, pharmaceutical compositions containing them and process for their preparation.. Thomae Dr K, January 28, 1987: EP0209707-A2 (29 worldwide citation)

2-Arylimidazoles of the formula in which R denotes a hydrogen atom or an alkyl group, Ar denotes a group of the formula A and B together with the two carbon atoms in between denote a group of the formula in which R1 denotes an alkylsulphenyl, alkylsulphinyl, alkylsulphonyl or alkylsulphoximino group ...


7
Reiffen Manfred Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Austel Volkhard Dr Dipl Chem, Eberlein Wolfgang Dr Dipl Chem, Kobinger Walter Prof Dr, Lillie Christian Dr, Noll Klaus Dr Dipl Chem, Pieper Helmut Dr Dipl Chem, Kruger Gerd Dr Dipl Chem, Keck Johannes Dr Dipl Chem: Benzazepines, process for their preparation and their application as pharmaceutical preparations.. Thomae Dr K, November 24, 1982: EP0065229-A1 (27 worldwide citation)

Compounds of general formula I (wherein A represents a group, wherein R7 represents a C1-3 alkyl group, and B represents a methylene or carbonyl group or A represents a -CO-CO- group and B represents a methylene group; E represents an optionally substituted ethylene, n-propylene or n-butylene group; ...


8
Bomhard Andreas Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Narr Berthod Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Lillie Christian Dr, Kobinger Walter Prof Dr, Diederen Willi Dr: Heteroaromatic amine derivatives, medicaments containing them and process for their preparation.. Thomae Dr K, June 8, 1988: EP0269968-A2 (24 worldwide citation)

Heteroaromatic amine derivatives of the formula in which n denotes the number 0 or 1, A denotes a methylene, carbonyl or thiocarbonyl group, B denotes a methylene, carbonyl or thiocarbonyl group, in which only one of the radicals A or B may represent a thiocarbonyl group and in this case the other o ...


9
Heider Joachim Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Austel Volkhard Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Van Meel Jacques Dr, Diederen Willi Dr: Imidazo derivatives, their preparation and medicines containing them. Thomae Dr K, June 25, 1986: EP0185345-A1 (21 worldwide citation)

Die Erfindung betrifft neue Imidazoderivate der allgemeinen Formel in der keiner, ein oder zwei der Reste A, B, C oder D ein Stickstoffatom, ein weiterer der Reste A, B, C oder D eine gegebenenfalls durch ein Halogenatom, eine Alkylmercapto-, Alkylsulfonyloxy-, Amino-, Alkylamino-, Dialkylamino- ode ...


10
Hauel Norbert Dr Dipl Chem, Austel Volkhard Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Reiffen Manfred Dr Dipl Chem, Diederen Willi Dr: Imidazole derivatives, their preparation and medicines containing these compounds.. Thomae Dr K, January 18, 1984: EP0098448-A2 (18 worldwide citation)

Neue Imidazolderivate der allgemeinen Formel in der A und B zusammen mit den beiden dazwischenliegenden Kohlenstoffatomen eine Gruppe der Formel wobei der Phenyl- und Pyridinring gegebenenfalls substituiert sein kann, R1 eine Alkansulfonyloxy-, Trifluormethansulfonyloxy-, Alkansulfonylamino-, Triflu ...



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