1

2
Hashihayata Takashi, Kawamura Mikako, Mitsuya Morihiro, Satoh Yoshiyuki: Novel aminopyrimidine derivatives as plk1 inhibitors. Banyu Pharmaceutical, Hashihayata Takashi, Kawamura Mikako, Mitsuya Morihiro, Satoh Yoshiyuki, BANYU PHARMACEUTICAL, July 10, 2008: WO/2008/081910 (12 worldwide citation)

The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein R1 and R2, which may be the same or different, are each a hydrogen atom, a halogen atom, a lower alkyl group which may be substituted, or a cyclopropyl group; R3 an ...


3
Kawamura Mikako, Hashihayata Takashi, Sunami Satoshi, Sugimoto Tetsuya, Yamamoto Fuyuki, Sato Yoshiyuki, Kamijo Kaori, Mitsuya Morihiro, Iwasawa Yoshikazu, Komatani Hideya: (Ja) 新規置換イミダゾール誘導体, (En) Novel substituted imidazole derivatives. Banyu Pharmaceutical, Kawamura Mikako, Hashihayata Takashi, Sunami Satoshi, Sugimoto Tetsuya, Yamamoto Fuyuki, Sato Yoshiyuki, Kamijo Kaori, Mitsuya Morihiro, Iwasawa Yoshikazu, Komatani Hideya, BANYU PHARMACEUTICAL, March 9, 2006: WO/2006/025567 (11 worldwide citation)

(EN) Compounds represented by the general formula [I] or pharmaceutically acceptable salts or esters thereof; and PLK1 inhibitors and anticancer drugs, containing the same: [I] wherein X1, X2, X3 and X4 are each independently C or N (with the proviso that zero to two of X1, X2, X3 and X4 are N); Y i ...


4
HASHIHAYATA TAKASHI, KAWAMURA MIKAKO, MITSUYA MORIHIRO, SATO YOSHIYUKI: [fr] NOUVEAU DÉRIVÉ DAMINOPYRIMIDINE COMME INHIBITEUR DE PLK1, [de] NEUES AMINOPYRIMIDINDERIVAT ALS PLK1-INHIBITOR, [en] NOVEL AMINOPYRIMIDINE DERIVATIVE AS PLK1 INHIBITOR. BANYU PHARMA, November 11, 2009: EP2116543-A1 (8 worldwide citation)

[en] The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein R 1 and R 2 , which may be the same or different, are each a hydrogen atom, a lower alkyl group, a cycloalkyl group, or the like R 3 and R 4 , which may be the ...


5
Hashihayata Takashi, Kawamura Mikako, Mitsuya Morihiro, Satoh Yoshiyuki: (Ja) plk1阻害剤としての新規アミノピリミジン誘導体, (En) Novel aminopyrimidine derivative as plk1 inhibitor. Banyu Pharmaceutical, Hashihayata Takashi, Kawamura Mikako, Mitsuya Morihiro, Satoh Yoshiyuki, BANYU PHARMACEUTICAL, July 10, 2008: WO/2008/081914 (3 worldwide citation)

(EN) Disclosed is a compound represented by the general formula (I) below, or a pharmaceutically acceptable salt or ester thereof. (In the formula, R1 and R2 may be the same or different and represent a hydrogen atom, a lower alkyl group, a cycloalkyl group or the like; R3 and R4 may be the same or ...


6
Yamada Koji, Hashihayata Takashi, Sako Koki, Sakuraba Shunji, Hashizume Terutaka: New carbapenem derivative. Banyu Pharmaceut, June 26, 2002: JP2002-179679 (2 worldwide citation)

PROBLEM TO BE SOLVED: To obtain a new carbapenem compound having an alkenyl group and to provide a method for producing the compound.SOLUTION: This compound is represented by formula (1) (wherein, R1 denotes hydrogen atom or methyl group; R2 denotes hydrogen atom or a protecting group of the hydroxy ...


7
Yamada Koji, Sakuraba Shunji, Hashihayata Takashi, Sako Koki, Hashizume Terutaka: Novel pyrrolidinylthio derivative. Banyu Pharmaceut, December 18, 2002: JP2002-363156 (2 worldwide citation)

PROBLEM TO BE SOLVED: To provide a new compound having metallo-β-lactamase inhibitory action. SOLUTION: The pyrrolidinylthio derivative is represented by formula (I) (wherein R1 is a lower alkyl, a cycloalkyl, an aryl, an aralkyl, a heteroaryl, a heteroarylalkyl, a lower alkoxy or aralkyloxy which m ...


8

9

10
Iwasawa Yoshikazu, Shibata Jun, Shimamura Tadashi, Kurihara Hideki, Mita Takashi, Kawanishi Nobuhiko, Hashihayata Takashi, Kawamura Mikako, Sagara Takeshi, Arai Sachie, Hirai Hiroshi: Selective inhibitors against cdk4 and cdk6 having aminothiazole skeleton. Banyu Pharma, February 21, 2007: EP1754706-A1

The present invention relates to a compound represented by Formula [I]: wherein X is O, S, NH or CH 2 ; Y 1 , Y 2 , Y 3 , Y 4 and Y 5 , which may be identical or different, are each CH or N; however, at least one of Y 1 , Y 2 , Y 3 , Y 4 and Y 5 is N; Z 1 and Z 2 , which may be identical or differen ...



Click the thumbnails below to visualize the patent trend.